Glycerin, anhydrous

SYNONYMS glycerin (anhydrous), glycerol, glycyl alcohol, 1,2,3-propanetriol, trihy-... 

Synonyms/Trade Names Glycerin (anhydrous) Glycerol Glycyl alcohol 1,2,3-Propanetriol Trihydroxypropane... 

When a few drops of anhydrous perchloric acid are added to ethanol, there is an immediate detonation. With ethylene glycol, glycerine and pentaerythritol, this acid forms liquids that detonate as soon as they are moved from one container to the next. The same is true for glycerine, when handled when in the presence of perchloric acid and lead (II) oxide. 

In an attempt to formulate an anhydrous, but water-soluble, semisolid base for potential ophthalmic use, five bases were studied [279]. The nonaqueous portion of the base was either glycerin or polyethylene glycols in high concentrations. The matrix used to form the phases included silica, Gantrez AN-139, and Carbopol 940. Eye irritation results were not reported, but the authors studied representative bases from that research report and found them to be quite irritating in rabbit eyes. The irritation is believed to be primarily due to the high concentration of the polyols used as vehicles. 

The primary use of anhydrous glycerin (Ophthalgan) is as an osmotic agent that is applied topically to reduce corneal edema. Orally administered glycerin (Glycerol, Osmoglyn) is used to reduce intraocular pressure and vitreous volume before ocular surgery. 

Ammonium nitrate, Chlorine gas Anhydrous ammonia, Chlorine gas, Water Glycerin, Sulfuric acid, Nitric acid Guanidine, Sulfuric acid, Water... 

Each 5 mL contains hydrocodone bitartarate 2.5 mg, acetaminophen 167 mg, and 7% alcohol. In addition, the liquid contains the following inactive ingredients citric acid anhydrous, ethyl maltol, glycerin, methylparaben,... 

Nasonex nasal spray, 50 meg is a metered-dose, manual-pump spray unit containing an aqueous suspension of mometasone furoate monohydrate equivalent to 0.05% w/w mometasone furoate, calculated on the anhydrous basis, in an aqueous medium containing glycerin, micro-... 

It also contains carboxymethylcellulose sodium citric acid, anhydrous flavors glycerin magnesium alu-... 

Experiments on the use of mixtures of nitric add with phosphoric anhydride showed this to be impracticable, since separate layers were formed with the phosphoric acid at the bottom and nitroglycerine remaining dissolved in the nitric add layer from which it had to be separated by adding water. Nor was replacement of sulphuric acid by anhydrous calcium nitrate of any practical value, as predpitation of nitroglycerine by the addition of water was necessary. The yield attained by application of both these methods does not exceed 2 parts of nitroglycerine from 1 part of glycerol. At the time when concentrated nitric add was very expensive, attempts were made to nitrate glycerine with a mixture of sulphuric acid and sodium nitrate (Huntley and Kessel [1]). However, this method found no practical use. 

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