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Antagonists glutamate receptors

Krystal JH, Cramer JA, Krol WF, et al Naltrexone in the treatment of alcohol dependence. N Eng J Med 343 1734-1739, 2001 Krystal JH, Petrakis IL, Limoncelli D, et al Altered NMDA glutamate receptor antagonist response in recovering ethanol-dependent patients. Neuropsychopharmacology 28 2020-2028, 2003a... [Pg.48]

Rockhold R., Oden G., Ho I., Andrew M., Farley J. Glutamate receptor antagonists block cocaine-induced convulsions and death. Brain Res. Bull. 27 721, 1991. [Pg.105]

A total synthesis of kaitocephalin, a glutamate receptor antagonist, was accomplished by employing a novel stereoselective C-C bond forming reaction between nitrone (345) and halide (344) as a key step (Scheme 2.148). The absolute configuration of kaitocephalin was confirmed to be 2 R,3 S,4 R,7 R,9 S (577). [Pg.250]

Markou A (2007) Metabotropic glutamate receptor antagonists novel therapeutics for nicotine dependence and depression Biol Psychiatry 61 17-22 Markou A, Paterson NE (2001) The nicotinic antagonist methyUycaconitine has differential effects on nicotine self-administration and nicotine withdrawal in the rat. Nicotine Tob Res. 3 361-373 MarttUa K, Raattamaa H, Ahtee L (2006) Effects of chronic nicotine administration and its withdrawal on striatal FosB/DeltaFosB and c-Fos expression in rats and mice. Neuropharmacology 51 44-51... [Pg.432]

In experimental studies, chronic antidepressant treatments have been shown to reduce the behavioural effects of the NMDA-glutamate receptor antagonist dizolcipine. This suggests that antidepressants may act as functional NMDA receptor antagonists and thereby reduce excitatory glutamate transmission which is mediated by NMDA receptors. [Pg.166]

Slassi A, Van Wagenen B, Stormann TM et al (2002) Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists. NPS Pharmaceuticals, Inc. WO/2002/ 068417... [Pg.196]

Chaki S, Yoshikawa R, Hirota S, et al (2004) MGS0039 a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity. Neuropharmacology 46 457-467... [Pg.287]

Loscher, W. (1998) Pharmacology of glutamate receptor antagonists in the kindling model of epilepsy. Prog Neurohiol 54 721-741. [Pg.32]

Zahn, P. K. and Brennan, T. J. Intrathecal metabotropic glutamate receptor antagonists do not decrease mechanical hyperalgesia in a rat model of postoperative pain, Anesth. Analg. 1998, 87, 1354-1359. [Pg.388]

Leem, J. W., Choi, E. J., Park, E. S., Paik, K. S. N-methyl-D-aspartate (NMDA) and non-NMDA glutamate receptor antagonists differentially suppress dorsal horn neuron responses to mechanical stimuli in rats with peripheral nerve injury, Neurosci. Lett. 1996, 211, 37-40. [Pg.420]

Woodward, R. M., Huettner, J. E., Tran, M., Guastella, J., Keana, J. F. W., Weber, E. Pharmacology of 5-chloro-7-trifluoromethyl-1,4-dihydro-2,3-quinoxalinedione a novel sytemically active ionotropic glutamate receptor antagonist, J. Pharmacol. Exp. Ther. 1995a, 275, 1209-1218. [Pg.428]

Shin-ya K, Kim J-S, Furihata K, Hayakawa Y, Seto H (1997) Structure of Kaitocephalin, a Novel Glutamate Receptor Antagonist Produced by Eupenicillium shearii. Tetrahedron Lett 38 7079... [Pg.425]

Frandsen A., Krogsgaard-Larsen P., and Schousboe A. (1990). Novel glutamate receptor antagonists selectively protect against kainic acid neurotoxicity in cultured cerebral cortex neurons. J. Neurochem. 55 1821-1823. [Pg.35]

Ikonomidou and Turski, 2002 Yi and Hazell, 2006). This suggests a cocktail of glutamate receptor antagonists, glutamate transporter inhibitors, antioxidants, and anti-inflammatory drugs may have beneficial effects in traumatic head injury. [Pg.169]

Glutamate Receptor Antagonists and Treatment of Neurological Disorders... [Pg.242]


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See also in sourсe #XX -- [ Pg.221 ]




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Antagonists glutamate

Glutamate receptor agonists/antagonists

Glutamate receptor antagonists and treatment

Glutamate receptor antagonists and treatment of neurological disorders

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Glutamate receptors

Metabotropic glutamate receptors antagonists

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