Global assessment

The objective of the global assessment is to present an assessment of plant safety that takes into account all unresolved shortcomings, all corrective actions and/or safety improvements and the plant strengths identified in the review of all PSR safety factors. 

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AKLAND ET AL. Global Assessment of Ambient Urban Air Quality... 

Kolodziejski J, Gasson C (2007) Water reuse markets 2005-2015. A global assessment and forecast. Global Water Intelligence, Oxford, UK... 

Camargo JA, Alonso A (2006) Ecological and toxicological effects of inorganic nitrogen pollution in aquatic ecosystems a global assessment. Environ Int 32 831-849... 

There are several approaches and methods to conducting a nutrition assessment, but one approach that has been validated is the Subjective Global Assessment (SGA).1 Application of the SGA requires gathering the data just listed and assessing these parameters (i.e., weight change, change in diet, GI symptoms, functional capacity, and physical examination)... 

Goal calorie and protein requirements Perform a subjective global assessment Take into consideration the patient s current clinical status, diagnoses, medications, etc. Total daily calories -25-30 kcal/kg per day, or -1 500-1 800 kcal/day Protein -1.5-2 g/kg per day of ideal body weight (-89-11 8 g protein/day) This patient has sepsis, diffuse peritonitis, and recent surgical procedures, target -1800 kcal/day and -11 0 g protein/day... 

Food and Agriculture Organization of the United Nations (FAO). Tackling Climate through Livestock A Global Assessment of Emissions and Mitigation Opportunities, Rome FAO. 2013. 

Other measures include the clinician s global assessment based on the patient s history of activities and limitations caused by OA, the Western Ontario and McMaster Universities Arthrosis Index, Stanford Health Assessment Questionnaire, and documentation of analgesic or NSAID use. 

The Physician Global Assessment can also be used to summarize erythema, induration, scaling, and extent of plaques relative to baseline assessment. 

The National Psoriasis Foundation Psoriasis Score incorporates quality of life and the patient s perception of well-being as well as induration, extent of involvement, the physician s static global assessment, and pruritus. 

Standardized assessment tools have also been constructed for ulcerative colitis. Elements in these scales include (1) stool frequency (2) presence of blood in the stool (3) mucosal appearance (from endoscopy) and (4) physician s global assessment based on physical examination, endoscopy, and laboratory data. 

Nriagu JO. 1989. A global assessment of natural sources of atmospheric trace metals. Nature 338 47-49. 

Figure 5.4 Global assessment of gene expression among various metabolic states. (From DeRisi, J. et al.. Science, 278, 680-686, 1997. With permission.)...

WHO/IPCS. 2002. Global assessment of the state-of-the-science of endocrine dismptors. International Programme on Chemical Safety. Geneva WHO. http /www.who.int/ipcs/publications/en/toc.pdf... 

This program aims to develop a global assessment of mercury and its compounds, including an outline of options for addressing any significant global adverse impacts of mercury. 

Patient reported outcomes (disability index, patient global assessment), physician assessments (tender/painful/swollen joints, physician s global assessment), objective measures (ESR, CRP) neutrophil counts baseline, q3mo, then quarterly qyr... 

Global assessment variables involve an investigator s overall impression of improvement or benefit. Usually this is done in terms of an ordinal scale of categories. While the guidelines allow such variables, experience shows that they... 

If objective variables are considered by the investigator when making a global assessment, then those objective variables should be considered as additional primary, or at least important secondary, variables. ... 

There may also be circumstances where a categorisation combines responses measured, on different domains of action for example to give a single dichotomous responder/non-responder outcome. There are connections here with global assessment variables. This approach is taken in Alzheimer s disease where the effect of treatment is ultimately expressed in terms of the proportion of patients who achieve a meaningful benefit (response) see the CPMP (1997) Note for Guidance on Medicinal Products in the Treatment of Alzheimer s Disease . In oncology. 

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