Ginsenoside from Panax ginseng

Corthout, J., Naessens, T., Apers, S., and Vlietinck, S. (1999). Quantitative determination of ginsenosides from Panax ginseng roots and ginseng preparations by thin layer chromatography-densitometry. /. Pharm. Biomed. Anal. 21,187-192. 

Glockl, I., Veit, M., and Blaschke, G. (2002). Determination of ginsenosides from Panax ginseng using micellar electrokinetic chromatography. Planta Med. 68,158-161. 

Schulten, H.-R., and Soldati, F. (1981). Identification of ginsenosides from Panax ginseng in fractions obtained by high-performance liquid chromatography by field desorption mass spectrometry, multiple internal reflection infrared spectroscopy and thin layer chromatography. J. Chromatogr. 212, 37-i9. 

Soldati, F., and Sticher, O. (1980). HPLC separation and quantitative determination of ginsenosides from Panax ginseng, Panax quinquefolium and from ginseng drug preparations. Planta Med. 38, 348-357. 

Soldati, F., and O. Sticher HPLC Separation and Quantitative Determination of Ginsenosides from Panax ginseng and from Ginseng Drug Preparations, 2nd Communication. Planta Medica 39, 348 (1980). 

Kenarova, B. et al., Immunomodulating activity of ginsenoside Rgl from Panax ginseng,... 

Akao, T., Kida, H., Kanaoka, M., Hattori, M., and Kobashi, K. (1998). Intestinal bacterial hydrolysis is required for the appearance of compound K in rat plasma after oral administration of ginsenoside Rbj from Panax ginseng.. Pharm. Pharmacol. 50,1155-1160. 

Asafu-Adjaye, E. B. and Wong, S. K. (2003). Determination of ginsenosides (ginseng saponins) in dry root powder from Panax ginseng, Panax quinquefolius, and selected commercial products by liquid chromatography Interlaboratory study. /. AOAC Int. 86, 1112-1123. 

Corbit, R. M., Ferreira, J. F. S., Ebbs, S. D., and Murphy, L. L. (2005). Simplified extraction of ginsenosides from American ginseng (Panax quinquefoUus L.) for high-performance liquid chromatography-ultraviolet analysis. /. Agric. Food Chem. 53, 9867-9873. 

Kanaoka, M., Kato, H., Shimada, F., and Yano, S. (1992). Studies on the enzyme immunoassay of bio-acive constituents in oriental medicinal drugs. VI. Enzyme immunoassay of ginsenoside Rbj from Panax ginseng. Chem. Pharm. Bull. 40, 314-317. 

Wang, J., Sakuma, T., Asafu-Adjaye, E., and Shiu, G. K. (1999). Determination of ginsenosides in plant extracts from Panax ginseng L. and Panax quinquefolius L. by LC/MS/MS. Anal. Ghem. 71,1579-1584. 

The effect of the major saponin from Panax ginseng (Araliaceae), ginsenoside Rbi (33), was investigated on rat liver protein phosphorylation. It was observed that 118, 63 and 34 kDa proteins were... 

Several ginsenosides, previously obtained from Panax ginseng and Panax notoginseng, were analyzed by HPLC. 

Ginsenoside Rgl, one of the major active ingredients isolated from Panax Ginseng, has neuroprotective effects in animal models with memory impairment. Intracerebroventricular (i.c.v.) okadaic acid (OKA), a potent phosphatase inhibitor, induced memory impairment, decrease of phospho-tau and phospho-GSK3p, and formation of p-amyloid deposits in the brain of treated rats. All these changes were reversed by Rgl [272],... 

Ginsenosides, a key component of Panaxginseng, are effective against AD. Karpagam et al. [399] reported that ginsenosides CK, FI, Rhl, and Rh2 are potential BACE1 inhibitors from Panax ginseng. 

Lee YJ, Chung E, Lee KY, Lee YH, Huh B, Lee SK (1997) Ginsenoside-Rgl, one of the major active molecules from Panax ginseng, is a functional ligand of glucocorticoid receptor. Mol Cell Endocrinol 133 135-140... 

Ginsenoside Rgl (27) from Panax ginseng also exerted a direct mitogenic effect when applied in vitro to microcultures of thymus cells. Again, this effect was greater with a lower dose (25 pg/ml) while a higher dose of Rgl (50 pg/ml) had no significant effect on thymocytes [59]. 

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