Nephrotoxicity gentamicin

AMELIORATION OF GENTAMICIN NEPHROTOXICITY BY GARLIC RELATION TO ANTIOXIDANT ENZYMES... [Pg.491]

Pedraza-Chaverri, J. et ah, Garlic ameliorates gentamicin nephrotoxicity relation to antioxidant enzymes, Free Radic. Biol. Med., 29, 602-611, 2000a. [Pg.666]

Gentamicin nephrotoxicity is attenuated by treatment with other aminoglycosides or with organic poly cations such as spermine, poly aspartate, and polylysine. Initially, competition for binding and intracellular uptake was the postulated mechanism of interaction between gentamicin and polycations. However, recent studies indicate that intracortical concentrations of gentamicin are not reduced in the pres-... [Pg.710]

Walker PD, Barri Y, Shah SV. Oxidant mechanisms in gentamicin nephrotoxicity. Ren Fail 1999 21(3-4) 433-42. [Pg.133]

In a few cases, gentamicin nephrotoxicity was associated with a Fanconi syndrome, with raised serum enzymes activities in the urine. Among these, murami-dase seemed to be especially useful in checking for proximal tubular dysfunction (30). [Pg.1501]

Wellwood JM, Tighe JR. Proceedings Evidence of gentamicin nephrotoxicity in patients with renal allografts. Br J Surg 1975 62(2) 156. [Pg.1504]

AN BH, Gentamicin nephrotoxicity in humans and animals some recent research, Gen Pharmac, 1995 26(7) 1477-87. [Pg.286]

Olbricht CJ, FinkM, Gutjahr E, Alterations in lysosomal enzymes of the proximal tubule in gentamicin nephrotoxicity. Kidney Int, 1991 39 639-46. [Pg.287]

Bennett WM, Mela-Riker LM, Houghton DC, Gilbert DN, Buss WC, Microsomal protein synthesis inhibition an early manifestation of gentamicin nephrotoxicity. Am J Physiol, 1988 24 F265-69. [Pg.288]

Zager RA, Gentamicin nephrotoxicity in the setting of acute renal hypoperfusion. Am J Physiol, 1988 23 F574-81. [Pg.288]

Houghton DC, Hartnett M, Campbell-Boswell M, Porter G, Bennett W, A light and electron microscopic analysis of gentamicin nephrotoxicity in rats. Am J Pathol, 1976,82 589-612. [Pg.288]

All BFI, Agents ameliorating or augmenting experimental gentamicin nephrotoxicity some recent research. Food Chem Toxicol, 2003,41 1447-52. [Pg.289]

Ramsammy LS, Josepovltz C, Lane BP, Kaloyanides, Polyaspartic acid protects against gentamicin nephrotoxicity In the rat, J Pharmacol ExpTherap, 1989, 250(1) 149-53. [Pg.289]

Swan SK, Gilbert DN, Kohihepp SJ, Leggett JE, Kohnen PW, Bennett WM, Duration of the protective effect of polyaspartic acid on experimental gentamicin nephrotoxicity, Antimicrob AgentsChemother, 1992, 36(11) 2556-58. [Pg.290]

AN BH, Bashir AK, Effect of superoxide dismutase treatment on gentamicin nephrotoxicity in rats, Gen Pharmac, 1996, 27(2) ... [Pg.290]

BennettWM, Elliott WC, Houghton DC, Gilbert DN, DeFehr J, McCarron DA, Reduction of experimental gentamicin nephrotoxicity in rats by dietary calcium loading, Antimicrob Agents Chemotherap, 1982, 22(3) 508-12. [Pg.290]

Quarum ML, Houghton DC, Gilbert DN, McCarron DA, Bennett WM, Increasing dietary calcium moderates experimental gentamicin nephrotoxicity, J LabClin Med, 1984,103(1) 104-14. [Pg.290]

Humes HD, Sastrasinh M, Weinberg JM, Calcium is a competitive inhibitor of gentamicin-renal membrane binding interactions and dietary calcium supplementation protects against gentamicin nephrotoxicity, J Clin Invest, 1982, 73 134-47. [Pg.290]

ZagerRA.Subclinical gentamicin nephrotoxicity a potential risk factor for exaggerated endotoxin-drivenTNF-a production. Am J Physiol, 2007, 293 F43-49. [Pg.291]

Gouvea W, Vaamonde CM, Owens B, Alpert H, Pardo V, Vaamonde CA. The protection against gentamicin nephrotoxicity in the streptozotocin-induced diabetic rat is not related to gender. Life sciences. 1992 51(22) 1747-58. [Pg.375]

The exact mechanism of aminoglycoside nephrotoxicity is unclear. As discussed above, release of lysosomal enzymes can contribute to altered cellular function. Hydroxy radicals may also play a role in aminoglycoside mitochondrial effects, since catalase inhibits in vitro alterations of mitochondrial function by gentamicin and the use of hydroxy radical scavengers or iron chelators reduces gentamicin nephrotoxicity in vivo. Additionally,... [Pg.1485]

D.L. Frazier, L.P. Dix, K.F Bowman, C.A. Thompson, J.E. Riviere. Increased Gentamicin Nephrotoxicity in Normal and Diseased Dogs Administered Identical Serum Drug Concentration Profiles Increased Sensitivity in Subclinical Renal Dysfunction. Journal of Pharmacology and Experimental Therapeutics, Vol. 239, pgs. 946-951,1986. [Pg.180]

Elliott WB, Eloughton DC, Gilbert DN, Baines-Elunter J, Bennett WM. Experimental gentamicin nephrotoxicity effect of strep-tozotocin-induced diabetes. J Pharm Exp Ther 1985 233 264-270. [Pg.165]

Bennett WM, Elartnett MN, Gilbert D, Eloughton D, Porter GA. Effect of sodium intake on gentamicin nephrotoxicity in the... [Pg.165]

Thompson JR, Simonsen R, Spindler MA, Southern PM, Cronin RE. Protective effect of KCI loading in gentamicin nephrotoxicity. Am J Kidney Dis 1990 15 583-591. [Pg.165]

Adelman RD, Spangler WL, Beasom F, Ishizaki G, Conzelman GM. Furosemide enhancement of experimental gentamicin nephrotoxicity comparison of functional and morphological changes with activities of urinary enzymes. J Infect Dis 1979 ... [Pg.165]

Cronin RE, Nix KL, Ferguson ER, Southern PM, Henrich WL. Renal cortex ion composition and Na-K-ATPase activity in gentamicin nephrotoxicity. Am J Physiol 1982 242 F477-F483. [Pg.168]

Morin NJ, Laurent G, Nonclercq D, Toubeau G, Heuson-Stiennon JA, Bergeron MG, Beauchamp D. Epidermal growth factor accelerates renal tissue repair in a model of gentamicin nephrotoxicity in rats. Am J Physiol 1992 263 F806-F811. [Pg.168]

Whiting, P. H., and P. A. Brown. 1996. Therelationship between enzymnria and kidney enzyme activities in experimental gentamicin nephrotoxicity. Renal Failure 18 899-909. [Pg.97]

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