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Generalized optimization criterion

Energetics of breathing is only one of many constraints that conflict with the metabolic cause of respiration. Another is the sensation of dyspnea which may be a limiting factor at high ventilatory levels [Oku et al., 1993]. A general optimization criterion may therefore include both energetic and dyspneic penalties as follows ... [Pg.183]

In order to extract the maximal energy out of the available foodstuff oxidative phosphorylation should operate at the state of optimal efficiency in vivo. Since a zero as well as an infinite load conductance both lead to a zero efficiency state, obviously there must be a finite value of the load conductance permitting the operation of the energy converter at optimal efficiency. For linear thermodynamic systems like the one given in equations (1) and (2) the theorem of minimal entropy production at steady state constitutes a general evolution criterion as well as a stability criterion.3 Therefore, the value of the load conductance permitting optimal efficiency of oxidative phosphorylation can be calculated by minimizing the entropy production of the system (oxidative phosphorylation with an attached load)... [Pg.145]

Factors may have associated values called levels of variations. Each state of a black box has a definite combination of factor levels. The more different states of the black box that exist, the more complex is the research subject. Formalization of preliminary information includes analysis of reference data, expert opinions and use of direct data, which enables correct selection of response, factors and null point or center of experiment. Factor limitations are also defined at this stage. If the research is linked with several following responses, then response limitations also have to be analyzed. The next phase refers to defining the research problem. When defining this problem one must keep in mind the research-subject model, and in a general case it is Eq. (2.1) that defines the link between the inlet and outlet of the black box. Defining the research problem is possible only now when its aim has been determined, the criteria established, the factors, limitations and null point defined. The problem is a simple one when only one response or optimization criterion is in... [Pg.168]

To optimize the flooding processes, we first have to select which optimization criterion to use. Generally, we choose incremental oil recovery factor as a criterion. Alternatively, we may choose maximum NPV as a criterion with economic analysis. The latter choice is more proper because it takes into account discounted cash flow. However, performing economic analysis requires more economic data that are generally not available. The criterion to be used depends on the objective. [Pg.383]

Reactors are considered in Sections 16.11.6.1 throngh 16.11.6.33 vessels are discussed in Sections 16.11.6.34 and 16.11.6.35. For most process eqnipment, equipment is sized based on the optimization criterion of cost. For reactors, the optimization criterion may be selectivity, yield, flexibility, ability to control, or cost. Section 16.11.6.1 lists the general rules of thumb. Section 16.11.6.2 gives examples of the reactor type based on the type of reaction. Sections 16.11.6.3 onward give rules of thumb organized by reactor type. [Pg.1410]

In summary, we create an initial random population of individuals and evaluate their fitness in relation to a chosen optimization criterion. In general the initial fitness is insufficient and a new generation has to be created using the techniques discussed. Evaluate fitness again and keep doing this routine until all individuals meet the optimization criterion. [Pg.106]

Optimization Methods Involving a Generalized Form of f(y). If some generalized two or three parameter function can be postulated for fiy) then general optimization methods can be applied to determine the values of the parameters which produce the best agreement, when incorporated in equation (26), with the dataset, g, e.g. a criterion for convergence of the best-fit could be the root-mean-square (r.m.s.) relative deviation ... [Pg.11]

The general formnlation of the problem of optimization of a material is the same as in the strnctnral optimization. An optimal material is described by a set of decisive variables x (i = 1,2,..., n) which minimize or maximize an optimization criterion or multiple criteria. The solutions should be within or on the border of the feasible domain. [Pg.451]

More correctly, the regression problem involves means instead of averages in (1). Furthermore, when the criterion function is quadratic, the general (usually nonlinear) optimal solution is given by y = [p u ], i.e., the conditional mean of y given the observation u . [Pg.888]

Thickener control philosophies are usually based on the idea that the Iindertlow density obtained is the most important performance criterion. The o ertlow clarity is also a consideration, but this is generally not as critical. Additional factors which must be considered are optimization of tlocciilant usage and protection of the raking mechanism. [Pg.1688]

The selection of cluster number, which is generally not known beforehand, represents the primary performance criterion. Optimization of performance therefore requires trial-and-error adjustment of the number of clusters. Once the cluster number is established, the neural network structure is used as a way to determine the linear discriminant for interpretation. In effect, the RBFN makes use of known transformed features space defined in terms of prototypes of similar patterns as a result of applying /c-means clustering. [Pg.62]

The ingredients of formulating optimization problems include a mathematical model of the system, an objective function that quantifies a criterion to be extremized, variables that can serve as decisions, and, optionally, inequality constraints on the system. When represented in algebraic form, the general formulation of discrete/continu-ous optimization problems can be written as the following mixed integer optimization problem ... [Pg.60]

In general it is not possible to develop a complete treatment scenario that is optimal technically, financially and also with respect to environmental sustainability. A solution has to be found which is economically and technically feasible and also satisfies the criteria of environmental sustainability to the greatest possible extent. An additional criterion for the selection of a complete closed loop water system can be obtained if the net environmental benefits are compared with the extra costs of the closed loop system. In this way the extra environmental benefits per unit investment costs or operating costs can be calculated. In the final selection of a closed loop water system aspects dealing with acceptability and public environmental awareness also play an important role. [Pg.249]


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