Genes/genetics

Kucho, K.-I., Y. Tsuchiya, Y. Okumoto et al. (2004). Construction of unmodified oligonucleotide-based arrays in the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1 Screening of the candidates for circadianly expressed genes. Genes Genet Syst 79 319-329. 

Wertman, K. F., Drubin, D. G., and Botstein, D. (1992). Systematic mutational analysis of the yeast ACT1 gene. Genetics 132, 337-350. 

TANAKA, A., TANO, S., CHANTES, T., YOKOTA, Y., SHIKAZONO, N., WATANABE, H., A new Arabidopsis mutant induced by ion beams affects flavonoid synthesis with spotted pigmentation in testa, Genes Genet. Syst., 1997, 72, 141-148. 

As with any patent application, to obtain a patent on a gene, genetic component (e.g., EST or SNP), or diagnostic or therapeutic method, the applicant must demonstrate the utility, novelty, and nonobviousness of the discovery. The applicant must also supply a disclosure and written description of the subject of the proposed patent that is sufficient in detail to show that the inventor had possession of the claimed subject matter at the time of application and to enable one skilled in the field to make use of the claimed subject matter. Although the fundamental elements of patentability have been in place for decades for protection of such innovations as new mechani-... 

Thiopurine methyltransferase (TPMT), 209. See also TMPT gene genetic variation in, 37-38 Thiopurine methyltransferase (TMPT) test, 90... 

In situations where there are errors in the chromosomes or genes, genetic disorders may result as shown in Exhibit A2.3. 

Allele-specific oligonucleotide Specific alleles of a gene Genetic counseling and DNA fingerprinting... 

Huntington s disease and the Fragiie X syndrome are singie-gene genetic diseases invoking tripiet repeats... 

Fig. 3. Identifying genes/genetic variants contributing to susceptibility to anticancer agent cytotoxicity.

Adapted from B-S. Kerem, I. M. Rommens, I. A. Buchanan, D. Markiewicz, T. K. Cox, A. Chakravarti, M. Buchwald, and L-C. Tsui, Identification of the cystic fibrosis gene Genetic analysis, Science 245 1075, 1989.)... 

Stadler, D.J. (1997). Ultraviolet-induced mutation and the chemical nature of the gene. Genetics 145, 863-865. 

Bisht, M. S. and Mukai, Y. (2000). Mapping of rDNA on the chromosomes of Eleusine speices by fluorescent in situ hybrization. Genes Genet. Syst. 75,343-348. 

Tompkins L. and McRobert S. P. (1989) Regulation of behavioral and pheromonal aspects of sex determination in Drosophila melanogaster by the Sex-lethal gene. Genetics 123, 535-541. 

Tate G, Li M, Suzuki T, Mitsuya T. A new mutation of the ATP-binding cassette, sub-family C, member 2 (ABCC2) gene in a Japanese patient with Dubin-Johnson syndrome. Genes Genet Syst 2002 77 117-121. 

Kerem B, Rommens JM, Buchanan JA, Markiewicz D, Cox TK, Chakravarti A, Buchwald M, Tsui LC. Identification of the cystic fibrosis gene genetic analysis. Science 1989 245 1073-1080. 

Nakamura T, Shimbata T, Vrinten P, Saito M, Yonemaru J, Seto Y, Yasuda H, Takahama M. Genes Genet. Syst. 2006 81 361. 

Cystic Fibrosis Gene Genetic Analysis Consortium (2001) Hum Mutations 4 167... 

Y. Oshima (1997). The phosphatase system in Saccharomyces cerevisiae. Genes Genet. Syst. 72, 323-334. 

T. S. Lendvay, D. K. Morris, J. Sah, B. Balasubramanian, and V. Lundblad. Senescence mutants of Saccharomyces cerevisiae with a defect m telomere replication identify three additional EST genes. Genetics, 144 (4), 1399-1412, 1996. 

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