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Genetics gene-nutrient interactions

The addition of prebiotics in food may offer other benefits by improving host absorption of minerals (like calcium or magnesium). Recent advances in this field show that inulin-type fructans enhanced calcium absorption primarily via the colonic mucosa in humans (Abrams et al. 2007). This effect may be partially due to the interaction of inulin type fmctans with the Fok 1 gene, a genetic modifier of calcium absorption, as well as due to the acidic environment caused by the production of SCFA, which may increase the solubility of minerals and thus enhance their absorption (Abrams etal. 2005). Crude fractions of chicory (a source of inulin) have shown improved bone parameters relative to native or reformulated inulin in rats, suggesting possible synergies between inulin-t5 e fructans and other nutrients (Demigne et al. 2008). [Pg.36]


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Gene / genetic

Gene/genetics

Genetic interaction

Interacting nutrients

Nutrient interactions

Nutrient-gene interactions

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