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Gastrointestinal stromal tumour

Retaspimycin (IPI-504) 70 (Infinity Pharmaceuticals) is being evaluated in a Phase III trial to treat patients with gastrointestinal stromal tumours that have failed previous treatments with imatinib and/or sunitinib.164 Retaspimycin 70 is a hydroquinone derivative of tanespimycin 68 that has significantly improved solubility while retaining potent Hsp90 binding activity.165 167... [Pg.336]

Prenen H, Deroose C, Vermaelen P, Sciot R, Debiec-Rychter M (2006) Establishment of a mouse gastrointestinal stromal tumour model and evaluation of response to Imatinib by small animal positron emission tomography. Anticancer Res 26 1247-1252... [Pg.140]

Verweij J, Casali P, Kotasek D et al (2007) Imatinib does not induce cardiac left ventricular failure in gastrointestinal stromal tumours patients Analysis of EORTC-ISG-AGITG study 62005. Eur J Cancer 43 974-978... [Pg.210]

Rossi G, Valli R, Bertolini F, et al. PDGFR expression in differential diagnosis between KIT-negative gastrointestinal stromal tumours and other primary soft-tissue tumours of the gastrointestinal tract. Histopathology. 2005 46 522-531. [Pg.538]

Parfitt JR, Rodriguez-Justo M, Feakins R, Novelli MR. Gastrointestinal Kaposi s sarcoma CD117 expression and the potential for misdiagnosis as gastrointestinal stromal tumour. [Pg.538]

Dhimes P, Lopez-Carreira M, Ortega-Serrano MP, et al. Gastrointestinal autonomic nerve tumours and their separation from other gastrointestinal stromal tumours an ultrastructural and immunohistochemical study of seven cases. Virchows Arch. 1995 426 27-35. [Pg.538]

Wong NA, Young R, Malcomson RD, et al. Prognostic indicators for gastrointestinal stromal tumours a clinicopathological and immunohistochemical study of 108 resected cases of the stomach. Histopathology. 2003 43 118-126. [Pg.538]

Debiec-Rychter M, Sciot R, Le Cesne A, et al. KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. Eur J Cancer. 2006 42 1093-1103. [Pg.540]

Wingen CB, Pauwels PA, Debiec-Rychter M, et al. Uterine gastrointestinal stromal tumour (GIST). Gynecol Oncol. 2005 97 970-972. [Pg.752]

O.S. Safety and efficacy of imatinib (ST1571) in metastatic gastrointestinal stromal tumours a phase 1 study. Lancet, 358 1421-1423, 2001. [Pg.1267]

Nishida, T. Hirota, S. Taniguchi, M. Hashimoto, K. Isozaki, K. Nakamura, H. Kanakura, Y. Tanaka, T. Takabayashi, A. Matsuda, H. Kita-mura, Y. Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nat. Genet., 19, 323-324 (1998)... [Pg.586]

Sunitinib Sutent Pfizer 2006 Multitargeted kinase inhibitor Imatinib-resistent gastrointestinal stromal tumour and advanced renal cell carcinoma 129... [Pg.118]

A patient with a recurrence of a gastrointestinal stromal tumour was given imatinib 400 mg daily without adverse effect. However, after 2 months, lansoprazole 15 mg daily was also given for dyspepsia and the patient developed bilateral eyelid oedema with hyperaemic conjunctivae and labial oedema. Both drugs were stopped, but on reintroduction the symptoms re-... [Pg.637]

Crohn s disease (Ulcerative) colitis Intestinal ischaemia Intestinal tuberculosis Intestinal invagination Diverticulitis Post-radiation enteritis Adenocarcinoma Gastrointestinal stromal tumour Intestinal metastases Appendicitis Intramural haematoma... [Pg.143]

GIST gastrointestinal stromal tumours, CUP cancer of unknown primary... [Pg.458]

Malignant Tumours of the Stomach and Duodenum 102 Gastric Carcinoma 102 Gastric Lymphoma 103 Gastrointestinal Stromal Tumour 103 Metastasis to the Stomach 104 Primary Carcinoma of the Duodenum 104 Secondary Involvement of the Duodenum 105 Bezoars 107 References 108... [Pg.89]

Fig. 5.24a-c. Gastrointestinal stromal tumour a Double-contrast barium meal showing a well-defined filling defect in the proximal stomach, b two selected views from a double-contrast barium meal of a second case. Note the central shallow ulcer, c The macroscopic specimen... [Pg.105]

See other pages where Gastrointestinal stromal tumour is mentioned: [Pg.1012]    [Pg.455]    [Pg.187]    [Pg.189]    [Pg.1012]    [Pg.117]    [Pg.224]    [Pg.82]    [Pg.102]    [Pg.103]    [Pg.103]    [Pg.113]    [Pg.127]    [Pg.137]    [Pg.137]    [Pg.137]    [Pg.139]    [Pg.144]    [Pg.159]    [Pg.65]    [Pg.66]   
See also in sourсe #XX -- [ Pg.51 , Pg.82 , Pg.102 , Pg.103 , Pg.105 , Pg.113 , Pg.116 , Pg.122 , Pg.137 , Pg.159 , Pg.174 ]



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