Fusarin

Locabiotal Locabiotal Locabiotal Locabiosol Fusaloyos Fusarine... 

Furoxane - Furazolidone Furoxone Furazolidone Fusaloyos Fusafungine Fusarine - Fusafungine Fusca - Clorprenaline... 

Kim, J.E. et ah. Putative polyketide synthase and laccase for biosynthesis of auro-fusarin in Gibberella zea, Appl. Environ. Microbiol., 71, 1701, 2005. 

Fumonisins, fusaric RAPD marker PCR acid, fusarin C, moniliformin, naphdioquinone pigments, beauvericin... 

Fumonisins, beauvericin, moniliformin, naphthoquinone pigments, fusaric acid, fusarin C, gibebyrones see fumonisin producers... 

International Agency for Research on Cancer (lARC) (1993). Toxins derived from Fusarium moniliforme Fumonisins Bi and Bz and Fusarin C. In "lARC Monographs on the Evaluation of the Carcinogenic Risks to Humans Some Naturally Occurring Substances Food Items and Constituents, Heterocyclic Aromaotic Amines and Mycotoxins," vol. 56, pp. 445 66. International Agency for Research on Cancer, Lyon, France. 

Fusarin C (see Toxins derived from Fusarium moniliforme)... 

The 2-methyl-5-n-butylpyridine was oxidated by selenium dioxide in pyridine to 5-n-butyl-2-pyridine carboxylic (fusarinic) acid, melting point 100-101°C. 

The mycotoxins with the greatest potential risk to human and animal health as food and feed contaminants are AFs, trichothecenes, fiimonisins, zearalenone, ochratoxin A, and ergot alkaloids.109 Other mycotoxins such as cyclopiazonic acid, sterigmatocystin, gliotoxin, citrinin, penitrems, patulin, fusarin C, penicillic acid, and PR... 

Phomopsin A (83 in Figure 18) was isolated from Phomopsis leptostromiformis as the hepatotoxic metabolite responsible for lupinosis, which is a disease in animals caused by ingestion of Lupinus species infected with the fungus.169 Penicillium species produce other significant mycotoxins such as penitrem A (84), PR toxin (85), and rubratoxin B (86).170 Fusarin C (87) and fusaproliferin (88) are known as mycotoxins produced by Fusarium... 

Figure 18 Structures of phomopsin A, penitrem A, PR toxin, rubratoxin B, fusarin C, and fusaproliferin.

Gelderblom WCA, Marasas WFO, Steyn PS, Thiel PG, Van der Merwe KJ, Rooyen HP, Vleggaar R, Wessels PL Structure elucidation of fusarin C, a mutagen produced by Fusarium moniliforme. J Chem Soc Chem Commun 1984 1984 122-124. 

Wiebe LA, Bjeldanes LF Fusarin C, a mutagen from Fusarium moniliforme grown on com. JFood Sci 1981 46 1424-1426. 

FURYL PHENYL KETONE see FQ0050 FUSARENONE X see FQROOO FUSARIC ACID see BSIOOO FUSARINIC ACID see BSIOOO FUSARIOTOXIN T 2 see FQSOOO FUSED BORAX see DXG035... 

Figure 3 Expression of lovB in A. nidulans, (a) in the absence and, (b) the presence of lovC (c) lovD catalyzed acyl transfer of lovB diketide 50 to monacolin ] 49 (d) proposed roles of FUSS domains in the biosynthesis of "pre-fusarin" 60.

Song ZS, Cox RJ, Lazarus CM, Simpson TJ. Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum. ChemBioChem. 2004 5 1196-1203. 

Fusarin C 4 is a mycotoxin produced by a number of Fusarium species. These organisms are often significant pests of cereals. Isotopic labelling studies indicated that it is biosynthesised from a polyketide chain fused to a C4N unit most probably derived from an amino acid. Once again the polyketide moiety is methylated with carbon atoms from SAM (22). 

The PKS most likely makes a heptaketide i.e. 6 cycles) with four appended methyl groups from SAM. The PKS must use the KS, AT, KR, DH and ACP domains in every cycle, but methylation only occurs after cycles I, 2, 3, and 5 (Scheme 1). Enoyl reduction occurs in none of the cycles - revealed by the polyunsaturated structure of fusarin C and consistent with the fact that the NADPH binding region of the ER appears to include a number of deleterious mutations. The polyketide intermediate IS probably remains attached to the PKS ACP at the end of its synthesis (Scheme 1). 

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