Fungal infections candidiasis

Systemic fungal infections Candidiasis, chronic mucocutaneous candidiasis, oral... 

Fungal infections, candidiasis, cryptococcosis PO 50 to 150 mg/kg/day in 4 equally divided doses. 

Indications Treatment of the following systemic fungal infections Candidiasis Chronic mucocutaneous candidiasis Oral thrush Candiduria Blastomycosis Coccidioidomycosis Histoplasmosis Chromomycosis Paracoccidioidomycosis... 

FIGURE 62-6. Candidiasis diaper dermatitis. Confluent erosions, marginal scaling, and "satellite pustules" in the area covered by a diaper in an infant. (From Wolff K, Johnson RA. Cutaneous fungal infections. Fitzpatrick s Color Atlas Synopsis of Clinical Dermatology. 5th ed. New York McGraw-Hill,... 

Oropharyngeal candidiasis (OPC) is a common fungal infection, usually associated with immune suppression. If left untreated, it will progress to more serious oral disease. Esophageal candidiasis, representing a serious progression of oropharyngeal candidiasis, is associated with increased morbidity. 

Since oropharyngeal and esophageal candidiasis are signs of immunocompromise, the immune status of the patient should be considered in the therapeutic care plan. For HIV-infected patients, this should also include an evaluation of the patient s antiretroviral therapy since fungal infections may represent deterioration in immune status. 

Response to antifungal therapy in invasive candidiasis is often more rapid than for endemic fungal infections. Resolution of fever and sterilization of blood cultures are indications of response to antifungal therapy. Toxicity associated with antifungal therapy is similar in these patients as described earlier with the caveat that some toxicities maybe more pronounced in crit-ically-ill patients with invasive candidiasis. Nephrotoxicity and electrolyte disturbances, with amphotericin B in particular, are problematic and may not be avoidable even with lipid amphotericin B formulations. Fluconazole and echinocandins are generally safer options, and are generally well tolerated. Decisions to use one class of agents over the other is principally driven by concerns of non-albicans species, patient tolerability, or history of prior fluconazole exposure (risk factor for non-albicans species.). 

Miconazole is an imidazole antifungal agent used as miconazole base or miconazole nitrate for the treatment of superficial candidiasis and of skin infections dermato-phytosis and pityriasis versicolor. The drug has also been given intravenously by infusion for the treatment of disseminated fungal infections. Miconazole can be given by mouth in a dose of 120-240 mg, as oral gel four times daily after food, for... 

Tapeworm infections are caused by Taenia solium. Tinea pedis causes the fungal infection known os athlete s foot. Yersinia pestis is implicated in plague, Candida albicans is responsible for candidiasis while Chlamydia frachomifis causes eye infections. 

Use primarily for treatment of patients with progressive and potentially fatal fungal infections. Do not use to treat noninvasive forms of fungal disease such as oral thrush, vaginal candidiasis, and esophageal candidiasis in patients with normal neutrophil counts. 

A significant decrease in mortality from deep-seated mycoses was noted among bone marrow transplant recipients treated prophylactically with fluconazole, but similar benefits have not been seen in leukemia patients receiving prophylactic fluconazole. Fluconazole taken prophylactically by end-stage AIDS patients can reduce the incidence of cryptococcal meningitis, esophageal candidiasis, and superficial fungal infections. 

Altered taste, vaginal candidiasis, fungal infection, dizziness, tongue discoloration Serious Reactions... 

Topical fungal infections, cutaneous candidiasis Topical Apply liberally 2 times/day, morning and evening. 

It is used orally for intestinal candidiasis, topically for oral, vaginal and cutaneous candidiasis and hospital treatment of progressive and potentially fatal systemic fungal infections. It is the gold standard of antifungal therapy. Flucytosine has supraadditive action with amphotericin B if the fungi is sensitive to both. It is also potentiated by rifampicin and minocycline. 

It is indicated in mucosal candidiasis, systemic candidiasis, crypttococcosis, prophylaxis of fungal infections following cytotoxic chemotherapy or radiotherapy maintenance to prevent relapse of cryptococcal meningitis in patients with AIDS sporotrichosis, histoplasmosis and vaginal candidiasis. 

Caspofungin Acetate injection For invasive candidiasis fungal infection... 

There is some concern, however, about fluconazole s effectiveness in treating deep, systemic fungal infections in severely ill patients.35 Hence, this drug can be combined with other antifungals such as amphotericin B to provide optimal treatment for certain cases of candidiasis and other severe fungal infections.4... 

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