Function three dimensional

With this information in hand, we may now consider how the -ATPase polypeptide chain might fold into its functional three-dimensional structure. First, regarding the actual number of membrane-spanning stretches, the available experimental data indicate only that each of the three membrane-embedded peptides must have an even number of and a minimum of two such stretches. However, hydropathy analysis by the method of Mohana Rao and Argos [48] suggests that the second mem-... 

All of the studies thus far carried out have clearly implicated lysine residues as essential in maintaining the functional integrity of the enzyme. As with all inhibition studies of the sort described below, a decision cannot be made concerning whether the implicated residues are actually in the active site of the enzyme or if they are indirectly involved in maintaining the protein in a catalytically functional three-dimensional state. It must be emphasized that we have not yet succeeded in identi-... 

A central backbone of straight tubular structures formed by the self-assembly of biotinylated lipids was used as a scaffold in order to construct functionalized three-dimensional, highly ordered helical arrays of streptavidin (Figure 7.38).259 260,261 Using these structures... 

RNA plays a central role in the life of cells. It is, therefore, important to understand how RNA forms functional native structures endowed with properties such as catalysis, binding of small-molecular-weight ligands, or recognition of proteins. Termed the RNA folding problem [1], the question is how the primary structure of RNA, a linear polynucleotide, encodes its functional three-dimensional (tertiary) structure. 

The Convergent Route to Globular Dendritic Macro molecules A Versatile Approach to Precisely Functionalized Three-Dimensional Polymers and Novel Block Copolymers [J. M. J. Frdchet, C. J. Hawker, K. L. Wooley, J. M. S.-Pure Appl. Chem. 1994, A31, 1627],... 

The a subunit is the most essential component of an ion channel. It is an integral membrane protein that requires a phospholipid environment to maintain a functional three-dimensional structure. Most a subunits are capable of forming functional channels when expressed alone in an artificial system, but they are often associated in native systems with transmembrane or cytosolic auxiliary subunits that modulate and fine-tune the properties of the channel. It is important to note that ion channel subunits often co-assemble in a tissue-specific manner and sometimes the expression patterns of individual subunits may be altered in disease. Therefore, when one is developing an assay using a heterologously expressed ion channel target, it is always preferable to employ a combination of subunits appropriate to the tissue and/or disease of interest. 

Protein folding is the physical process by which a polypeptide folds into its characteristic and functional three-dimensional structure. 

If primary structure is amino-acid residue sequence, then secondary structure represents the first major steps towards a functional three dimensional structure. Secondary structures are essentially transient three dimensional structural elements that polypeptides may form in solution and that can interlock or dock together forstability. Polypeptides are capable of forming remarkably beautiful helical structures that are known as the right-handed a helix (qr)... 

Self-assembly is a demonstrated strategy to achieve interconnections and to constract tliree-dimensional circuits and stractures. Self-assembly of millimeter-scale polyhedra, with surfaces patterned with solder dots, and light-emitting diodes, generated electrically functional, three-dimensional networks. The patterns of dots and wues controlled the structure of the networks formed. Both parallel and serial connections were formed. This self-assembly mechanism may be suitable for generating other starctures for implantates and biosensors. 

Anti Jander function, three-dimensional diffusion [(l + ar)i-lf 0.971185 0.00000936... 

Functional Three-dimensional Micromachined Electrochemical Devices... 

Describe the types of intermolecular forces that govern the folding of a protein molecule into its physiologically functioning three-dimensional state. 

Sekine, H., Shimizu, T., Sakaguchi, K., Dobashi, L, Wada, M., Yamato, M., et al. (2013). In vitro fabrication of functional three-dimensional tissnes with perfusable blood vessels. Nature Communications, 4,1399. 

The effects of interchain interactions on the stabilization of polarons in conjugated polymers have been considered in density functional three-dimensional calculations performed on PPV [41 ]. These calculations indicate that the polaronic effects as modeled in the isolated chain models may be considerably less strong when interchain interactions are taken into account, and the same concern has been raised by Emin [42,43]. 

Jia, B., Buso, D., van Embden, J., Li, J and Gu, M. (2010) Highly non-linear quantum dot doped nanocomposites for functional three-dimensional structures generated by two-photon polymerization. Adv. Mater., 22, 2463-2467. 

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