Foods: Liver

As a coen2yme component in tissue oxidation—reduction and respiration, riboflavin is distributed in some degree in virtually aU naturally occurring foods. Liver, heart, kidney, milk, eggs, lean meats, malted barley, and fresh leafy vegetables are particularly good sources of riboflavin (see Table 1). It does not seem to have long stabiUty in food products (8). 

COMMON FOODS liver, fish, fortified milk, eggs, green leafy vegetables. 

Source (Food) Liver, eggs, milk, meats and fish. Commercial source produced by microbial action on various nutrients (spent antibiotic liquors, sugar-beet molasses, whey), also from sewage sludge. 

Biotin is widely distributed in foods liver, milk, yeast, oilseeds and vegetables are rich sources. However, in some foods, much of the bound vitamin may not be released during digestion and hence may be imavailable. Studies with chicks and pigs have shown that the availability of biotin in barley and wheat is very low, whereas the biotin in maize and certain oilseed meals, such as soya bean meal, is completely available. 

Rats fed laboratory chow versus feeding with "people" foods fruits, baby food, liver, bread, milk <1 % laboratory chow up to 20% with "people" foods Lower uptakes in adult rodents more due to diet, not test species Kostial and Kello (1979)... 

A large number of polycyclic aromatic hydrocarbons are known Many have been synthesized m the laboratory and several of the others are products of com bustion Benzo[a]pyrene for example is present m tobacco smoke contaminates food cooked on barbecue grills and collects m the soot of chimneys Benzo[a]pyrene is a carcinogen (a cancer causing substance) It is converted m the liver to an epoxy diol that can induce mutations leading to the uncontrolled growth of certain cells... 

Decreased production of yolk protein resulting from inhibition of either ovarian or liver function presents the fish with a similar choice to that resulting from decreased food availability. It can produce the same number of smaller eggs, or a smaller number of eggs of normal size, but the mechanism by which that choice is made is unclear. Since the decreased nutrient content of small eggs will result in smaller larvae with a decreased survival rate, the net result in both cases may be a... 

The first hormonal signal found to comply with the characteristics of both a satiety and an adiposity signal was insulin [1]. Insulin levels reflect substrate (carbohydrate) intake and stores, as they rise with blood glucose levels and fall with starvation. In addition, they may reflect the size of adipose stores, because a fatter person secretes more insulin than a lean individual in response to a given increase of blood glucose. This increased insulin secretion in obesity can be explained by the reduced insulin sensitivity of liver, muscle, and adipose tissue. Insulin is known to enter the brain, and direct administration of insulin to the brain reduces food intake. The adipostatic role of insulin is supported by the observation that mutant mice lacking the neuronal insulin receptor (NDRKO mice) develop obesity. 

Biotin can be synthesized by the human colon flora. The question to which extent this production contributes to covering the host-organism s requirements is, however, subject to discussion. In most foods of animal origin as well as in cereals, biotin prevails in the protein (= enzyme)-bound form as e-N-biotinyl-L-lysine (= biocytin). Brewer s yeast, liver, soya beans, and peanuts number among the biotin rich foods [1]. 

---