Liver food-entrainment

Okamura Shibata s group shows that SCN-lesioned animals are food entrainable, and CLOCK in the liver is oscillating (Kara et al 2001). 

Koshash Is the liver of a SCN-lesioned animal entrainable with food ... 

Use of the Per-luc rat model made possible studies on the role of food in the entrainment of these and other peripheral clocks (Stokkan et al 2001). Rats were fed under restriction during the day. Organ explants from these rats were then cultured and the phases of the Per-luc rhythm were shifted by 12 hours in the liver (Fig. 3), and somewhat lesser amounts in stomach and colon (Fig. 4B). The SCN was completely unaffected by the feeding schedule. 

Stephan FK 2002 The other circadian system. Food as a Zeitgeber. J Biol Rhythms 17 284-292 Stephan FK, Swann JM, Sisk CL 1979 Anticipation of 24-hr feeding schedules in rats with lesions of the suprachiasmatic nucleus. Behav Neural Biol 25 346—363 Stephan FK, Zucker I 1972 Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions. Proc Natl Acad Sci USA 69 1583-1586 Stokkan KA, Yamazaki S, Tei H, Sakaki Y, Menaker M 2001 Entrainment of the circadian clock in the liver by feeding. Science 291 490-493... 

---