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Fluticasone propionate/salmeterol

Chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis For the twice-daily maintenance treatment of airflow obstruction in patients with COPD associated with chronic bronchitis. Fluticasone propionate/salmeterol 250 meg per 50 meg twice daily is the only approved dosage for the treatment of COPD associated with chronic bronchitis. Fligher doses, including fluticasone propionate/salmeterol 500 meg per 50 meg, are not recommended. [Pg.822]

Administer by the orally inhaled route only. The maximum recommended dose of fluticasone propionate/salmeterol is 500 meg per 50 meg twice/day. [Pg.822]

Patients receiving fluticasone propionate/salmeterol twice daily should not use salmeterol or other inhaled, long-acting 2-agonists (eg, formoterol) for... [Pg.822]

Recommended Starting Doses of Fluticasone Propionate/Salmeterol for Asthma Patients (Age 12) Taking Inhaled Corticosteroids ... [Pg.823]

Current daily dose of inhaled corticosteroid Recommended strength and dosing schedule of fluticasone propionate/salmeterol... [Pg.823]

Do not use fluticasone propionate/salmeterol for transferring patients from systemic corticosteroid therapy. ... [Pg.824]

Children 4 to 11 years of age - For patients 4 to 11 years of age who are symptomatic on an inhaled corticosteroid, the dosage is 1 inhalation of fluticasone propionate/salmeterol 100 meg per 50 meg twice/day (morning and evening, approximately 12 hours apart). [Pg.824]

Fluticasone Propionate Salmeterol Xinafoate (Advair Diskus, Advair HFA, 45/21, 115/21,230/21 Inhaled Aerosol) Ipratropium (Atrovent HFA, Atrovent Nasal) Nedocromil (Tilade) Tiotropium (Spiriva) Triamcinolone (Azmacort)... [Pg.56]

Fluticasone Propionate Salmeterol Xinafoate (Advair Diskus, Advair HFA,... [Pg.55]

FLUTICASONE PROPIONATE/SALMETEROL (Atvair diskus powder for inhalation 100 meg fluticasone propionate, 50 meg salmeterol, powder for inhalation 250 meg fluticasone propionate, 50 meg salmeterol, powder for inhalation 500 meg fluticasone propionate, 50 meg salmeterol)... [Pg.282]

FergusonGT, AnzuetoA,FeiR,Emmett A, Knobil K, Kalberg C. Effect of fluticasone propionate/salmeterol (250/50 microg) or salmeterol (50 microg) on COPD exacerbations. Respir Med 2008 102(8) 1099-108. [Pg.372]

Synthesis of fluticasone propionate 14.3 Synthesis of salmeterol xinafoate 14.4 Synthesis of montelukast sodium 14.5 References... [Pg.230]

A 23-year-old man, with a history of asthma, house dust mite allergy, and rhinoconjunctivitis, presented with acute respiratory symptoms. He was given oral cetirizine, inhaled salmeterol, and fluticasone propionate, and oral prednisone 40 mg/day for 1 week and 20 mg/day for 1 week. His asthma recurred when prednisone was withdrawn and he took oral prednisone 60 mg/day for 1 week and 40 mg/day for 1 week. He also took montelukast 10 mg/day. He then developed severe peripheral edema with a gain in weight of 13 kg. Prednisone was withdrawn and his edema resolved. Montelukast was continued. [Pg.54]

A 32-year-old woman s asthma regimen was changed from budesonide to fluticasone propionate 500 micrograms/day and salmeterol (44). Eight months later, she was evaluated because of excessive bodyweight gain her serum cortisol concentration was 16 nmol/1. Fluticasone propionate was replaced with nedocromil and 1 month later her serum cortisol concentration had normalized. [Pg.76]

Seretide is a combination therapy consisting of fluticasone propionate and salmeterol. It is marketed by GSK for the treatment of asthma. Fluticasone is the chiral component and a steroid derivative. [Pg.598]

Nelson, H. S., Chapman, K. R., Pyke, S. D., Johnson, M., and Pritchard, J. N. (2003), Enhanced synergy between fluticasone propionate and salmeterol inhaled from a single inhaler versus separate inhalers, J. Allergy Clin. Immunol., 112,29-36. [Pg.714]

Aubier M, Pieters WR, Schlosser NJ, Steinmetz KO. Salmeterol/fluticasone propionate (50/500 microg) in combination in a Diskus inhaler (Seretide) is effective and safe in the treatment of steroid-dependent asthma. Respir Med 1999 93(12) 876-84. [Pg.3103]

Chapman KR, Ringdal N, Backer V, Palmqvist M, Saarelainen S, Briggs M. Salmeterol and fluticasone propionate (50/250 microg) administered via combination Diskus inhaler as effective as when given via separate Diskus inhalers. Can Respir J 1999 6(1) 45-51. [Pg.3103]

The best way to get a quick overview of the real-world metabolism is to see how popular prescription drugs are metabolized. Figure 9.21 outlines the major metabolic sites for the world s 10 top-selling small molecule prescription drugs of 2006. The appearance of 11 structures in this top 10 list is no mistake, since both fluticasone propionate and salmeterol xinafoate (counterion not shown) are components of the 2 drug, Advair, used for the treatment of asthma. Only the one or two most predominant primary metabolic processes are shown. [Pg.380]


See other pages where Fluticasone propionate/salmeterol is mentioned: [Pg.821]    [Pg.822]    [Pg.822]    [Pg.823]    [Pg.824]    [Pg.821]    [Pg.822]    [Pg.822]    [Pg.823]    [Pg.824]    [Pg.932]    [Pg.623]    [Pg.205]    [Pg.231]    [Pg.232]    [Pg.63]    [Pg.590]    [Pg.434]    [Pg.205]    [Pg.231]    [Pg.919]    [Pg.6]    [Pg.632]    [Pg.1982]   


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