Flexibility imperative

Drivers of Supply Chain Change Six drivers of change The role of innovation The flexibility imperative Criteria for a great supply chain... 

Flexibility imperative The advantage gained from effective responses to market and technology changes Examples include product mix, volume, and base product features... 

Table 3.1 presents a working definition of each driver. Figure 3.1 models the connections among them. Innovation, in Figure 3.1, pushes the whole process forward, so we place it first in our sequence. Innovation is external to the supply chain system. It pushes supply chain participants to continuously improve their chains. The three drivers — Extended Product Design, Globalization, and Flexibility Imperative — shape the direction, scope, and form of products and services and the supply chains needed to deliver them. 

The last driver arising from innovations is what we call the supply chain flexibility imperative. Absence of flexibility infers a static supply chain that is unable to flex as environmental changes require. This is based on the assumption that few organizations do not face environmental change of some sort. Lack of flexibility also characterizes supply chains that serve different customers who have different needs with a one-size-fits-all approach. They fail to take into account the needs of different customer segments. 

An obvious example is production interruptions and shortages. If any one of the supply chain links breaks and fails to deliver, then the entire chain is threatened. Such a company or supply chain lacks flexibility. Section 3-5 described the flexibility imperative. Variability of any type reinforces the need for designing flexibility into the chain, widening the lowest-cost operating zone. 

While sample documentation and tracking protocols, as well as QA/QC procedures, have been in place and in effect for many years, their application is tailored to the needs and resources of each individual project, with some exploratory or field-feedback studies requiring much less verification than other regulatory or complaint series. Flexibility in experimental design is imperative if a facet of an investigation is to be completed in accordance with its significance and allocated resources. However, since several of our programs are potentially answerable to GLP s, it was deemed important that the laboratories current level of compliance be established so as to accurately measure the full fiscal and scientific impact to be felt if we should attempt to institute a formal GLP structure. 

Cost allocation schemes were replaced by more flexible service contracts that made costs and services rendered much more transparent. These contracts range from more traditional time- and mate-rials-based arrangements to full service agreements, where the service providers and their customers agree on certain output parameters such as uptime/plant performance rather than on input parameters such as maintenance cost. Price negotiations with the customers became the key imperative of this transition phase. 

In summary, these results show that the role of the monomer is twofold as a cosurfactant, it increases the flexibility and the fluidity of the interface, which favors the formation of a bicontinuous microemulsion. An an electrolyte, it induces the latter structure. These two conditions are imperative. Similar water-oil-surfactant (s) systems do not lead to bicontinuous microemulsions in the absence of monomers or salts (when the monomer is not itself an electrolyte). 

At the end of this chapter it may be realized how untenable this until recently most common attitnde of ignoring the H2O molecule is, and how imperative it becomes to know much more about some of its subtle properties. This is certainly no easy task and around 20 years after Maddox (5) rang the bell to stop the attitude he called a scandal, this field of research is still in an early stage of development. We know this molecule plays an important role when it is embedded in macromolecules. This role even becomes vital when it comes to biological molecules. We are now starting to have ideas about this role. It is no doubt due to the exceptional ability this molecule has to develop around it an extended, dense and flexible 3D H-bond network by association with other HjO molecules, even a very few of them. This exceptional ability is itself a consequence of the exceptional structure of the H2O molecule, which, as illustrated in Figure 8.1, has two H-bond donor sites and two H-bond acceptor sites. A preliminary, um-efmed answer to the question How is it that life occurs only in presence of HjO molecules is this H2O molecules are the only molecules, along with HDO and DjO, that are able to provide inside macromolecules such an extended 3D H-bond network that they always develop around them. 

It is imperative to examine the effect of carcinogen-DNA adducts on the topology as well as conformation of DNA, since these properties are believed to influence the specific DNA interactions. From the spectroscopic studies (uv, CD, LD) it can be inferred that both B and Z forms of polynucleotides can covalently react with BaPDE with a very low affinity for the Z form [124, 127-128]. In fact, both diastereomers favour and preserve B-like conformations around the adduct site even at 4.5M NaCl. This might introduce flexibility in the poly (dG-dC). poly (dG-dC) structure manifested by a reduced LD signal [129]. Thus anri-BaPDE adduct formation may affect the behaviour of DNA selectively not only at the... 

Flexibility specifications are imperative because they drive the design of supply chain processes and shape collaboration with supply chain partners. Static specifications are not acceptable the Upton method makes possible definition of ranges of operations and expectations for customer service. Also, many CEOs seek some kind of visual cockpit for their operations. One based on defined flexibility parameters such as those in the example is an excellent start. 

Polymers used in a typical mobile phone include acrylonitrile-butadiene-styrene (ABS) or PC for the outer case because of their weight reducing qualities and their durability. Good transparency is imperative for the screen for which PC or PMMA may be chosen. Connector manufacturers have several options with polybutylene terephthalate (PBT) and polyamide (PA) providing stability. Eor safety reasons elastomers provide the raw material for antennas. PCB base material is invariably an epoxy resin because it offers heat resistance and design flexibility. The components themselves may... 

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