Field asymmetric ion mobility spectrometry FAIMS

The first description of a differential mobility spectrometer is shown in Fig. 9 with a schematic from the 1993 article by Buryakov et al. [8-10], Subsequently, the technology from this team was migrated to the USA [39] and then Canada [40] as field asymmetric ion mobility spectrometry (FAIMS) with a cylindrical design for the analyzer. The FAIMS analyzer was attached to a mass spectrometer [41], and a line of study on large instrumentation was begun where the FAIMS was an ion filter for the mass spectrometer in environmental and biological studies [42 14], Refinements were made and a commercial inlet for mass spectrometers was introduced [45], but no determinations with... 

Boyle, B., Hart, M., Koehl, A., Ruiz-Alonso, D., Taylor, A., Wilks, A., New territory in field asymmetric ion mobility spectrometry enabling higher operational field strengths using a MEMS fabricated FAIMS device. Proceedings of the 59th Pittcon Conference, New Orleans, LA (03/2008). 

Atmospheric pressure ionization-field asymmetric ion mobility spectrometry-mass spectrometry (API-FAIMS-MS) can find CWAs in food. GD, GB, tabun (GA), and others were spiked into water, oU, commeal, and honey at low microgram per gram levels [55]. This methodology was chosen to achieve low nanogram per gram detection limits for each sample matrix and lower analysis times to 3 min or less. 

Kolakowski, B. M., Lustig, D., and Purves, R. W. (2004). Separation and quantitation of caffeine metabolites by high-field asymmetric waveform ion mobility spectrometry (FAIMS). 

Kolakowski, B.M. Mester Z., Review of applications of high-field asymmetric waveform ion mobility spectrometry (FAIMS) and differential mobility spectrometry (DMS), Analyst 2001,132(9), 842-864. 

McCooeye, M.A. Ells, B. Barnett, D.A. Purves, R.W. Guevremont, R., Quantitation of morphine and codeine in human urine using high-field asymmetric waveform ion mobility spectrometry (FAIMS) with mass spectrometric detection, J. Anal. Toxicol. 2001, 25, 81-87. 

Gabryelski, W. Froese, K.L., Rapid and sensitive differentiation of anomers, linkage, and position isomers of disaccharides using high-field asymmetric waveform ion mobility spectrometry FAIMS, J. Am. Soc. Mass Spectrom. 2003, 14, 265-277. 

Over the last decade, scientific and engineering interests have been shifting from canventional ion mobility spectrometry (IMS) to field asymmetric waveform ion mobility spectrometry (FAIMS). Differential Ion Mobility Spectrometry Nonlinear Ion Transport and Fundamentals of FAIMS explores this new analytical technology that separates and characterizes ions by the difference between their mobility in gases at high and low electric fields. It also covers the novel topics of higher-order differential IMS and IMS with alignment of dipole direction. 

This is the first book on differential ion mobility spectrometry (IMS), an analytical technique also called field asymmetric waveform ion mobility spectrometry (FAIMS) and, on occasion, several of the altemafive names mentioned in the Introduction. These terms refer to the evolving methods for separation and characterization of ions based on the nonlinearity of their motion in gases under the influence of a strong electric field. 

Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS).209... 

FIELD ASYMMETRIC WAVEFORM ION MOBILITY SPECTROMETRY (FAIMS)... 

A rather different way of exploiting differences in ion mobilities through a buffer gas is embodied in so-called High Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS), in which the physical property... 

Whereas high-field asymmetric waveform ion mobility spectrometry (FAIMS) is able to separate ions in a manner similar to IMS, the method cannot be considered an alternative to IMS in the context (elucidation of ion structure) discussed here, since electric fields employed in FAIMS are way above the low-field limit. " - However, two other newer developments, traveling-wave IMS and overtone ion mobility spectrometry (OMS), are worth mentioning here briefly. 

Robinson, E. W. Sellon, R. E. Williams, E. R. Peak deconvolution in high-field asymmetric waveform ion mobility spectrometry (FAIMS) to characterize macromolecular conformations. Int. J. Mass Spectrom. 2007, 259, 87-95. 

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