Exchange-induction

Mitomycin C was found to have broad activity against a range of tumors and has been used clinically since the early 1960s [14, 15]. It causes many specific cellular effects, including inhibition of DNA synthesis, recombination, chromosome breakage, sister chromatid exchange, induction of DNA repair, and induction of... 

Contributions Methods Electrostatics Exch.-rep. Correlation corrections Induction Exchange- induction Ind. and exch-Ind. Correlation corrections Dispersion ... 

Parodi, S., M.Taningher, P.Russo, M.Pala, M.Tamaro, and C.Monti-Bragadin. 1982. DNA damage in liver, kidney, bone marrow and spleen of rats and mice treated with commercial and purified aniline as determined by alkaline elution assay and sister chromatid exchange induction. Cancer Res. 42 2277—2283. 

Wilmer, J.L., A.D.Kligerman, and G.L.Erexson. 1981. Sister chromatid exchange induction and cell cycle inhibition by aniline and its metabolites in human fibroblasts. Environ. Mutagen. 3 627-638. 

Latt, S.A. and Loveday, K.S. (1978). Characterization of sister chromatid exchange induction by 8-methoxypsoralen plus UV light. Cytogenet. Cell Genet. 21 184-200. 

Chlordecone (1.67-10.00 mg/L) increased the frequency of sister chromatid exchange in CHO cells but only in the absence of S9 activation and only in the presence of cell-cycle delay the results were confirmed in a repeat trial (Galloway et al. 1987). By contrast, chlordecone alcohol was negative for sister chromatid exchange induction both with and without S9 activation (Galloway et al. 1987). Subcytotoxic doses of mirex did not induce unscheduled DNA synthesis in primary hepatocytes recovered from rats, mice, or hamsters (Maslansky and Williams 1981 Williams 1980). Similar results were obtained by Probst et al. (1981) using primary rat hepatocytes exposed to 1,000 pmol/L mirex. Chlordecone was also uniformly negative in unscheduled DNA synthesis assays of primary rat hepatocytes (Probst et al. 1981 Williams 1980). 

Erexson GL, Wilmer JL, Kligerman AD. 1985. Sister chromatid exchange induction in human lymphocytes exposed to benzene and its metabolites in vitro. Cancer Res 45 2471-2477. 

Speit G, Vogel W, Wolf M Characterization of sister chromatid exchange induction by hydrogen peroxide. Environ Mutagen 4 135-142, 1982... 

Landi, S., Ponzanelli, I., Hirvonen, A., Norppa, H. Barale, R. (1996b) Repeated analysis of sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes effect of glutathione S-transferase Tl and Ml genotype. Mutat. Res., 351, 79-85... 

Uuskula, M., Jarventaus, H., Hirvonen, A., Sorsa, M. Norppa, H. (1995) Influence of GSTMl genotype on sister chromatid exchange induction by styrene-7,8-oxide and l,2-epoxy-3-butene in cultured human lymphocytes. Carcinogenesis, 16, 947-950... 

Mehnert, K., Vogel, W.. Benz. R. Sc Speit, G. (1984a) Different effects of mutagens on sister chromatid exchange induction in three Chinese hamster cell lines. Environ. Mutag.. 6. 573— 583... 

Trichloroethane covalently bound to DNA, RNA and protein in mice and rats but did not induce micronuclei or abnormal sperm head morphology in mice in vivo. It induced chromosomal aberrations and cell transfonnation in mammalian cell cultures and it showed inconclusive evidence of sister chromatid exchange induction. It did not induce unscheduled DNA synthesis or gene mutation in mammalian cells in vitro. 

The second-order exchange energy in the SRS theory, defined as Ef = (2) (2) eXCn sRS- poi, separates naturally into two contributions exchange-induction and... 

The exchange-induction energy is an energetic effect resulting from the antisym-metrization of the induction wave function,... 

In the original paper of Morokuma258 the sum of the exchange-induction and exchange-deformation contributions was ascribed to the charge transfer. 

The second-order exchange nonadditivity splits into exchange-induction, exL-ind and exchange-dispersion, h-disP> three-body contributions ... 

Equation (1-239) relates the interaction-induced part of the dipole moment of the complex AB to the distortion of the electron density associated with the electrostatic, exchange, induction, and dispersion interactions between the monomers. The polarization contributions to the dipole moment through the second-order of perturbation theory (A/a, A/a, and A/a ) have an appealing, partly classical, partly quantum, physical interpretation. The first-order multipole-expanded polarization contribution (F) is due to the interactions of permanent multipole moments on A with moments induced on B by the external field F, and vice versa. The terms... 

The first analytical three-body potential for A HCl was proposed by Hutson and collaborators [75] on the basis of semiempirical considerations. It consisted of three terms exchange, induction, and dispersion nonadditivities. The dispersion nonadditivity was represented by Eq.(19), and the induction nonadditivity as an interaction of multipoles induced... 

He2, while Williams et al [47] have shown that the exchange-dispersion term is negligible in the repulsive region, but that of exchange-induction is not. 

Hiysically, one can think of rather specific second order effects caused by the exdumge forces". For instance, the Pauli exchan repulsion between two closed sheU systems leads to on outward polarizatkm of the electron douds which lowers this exchange rqxilsioa. This energy lowering, which may be called exchange-induction energy, has indeed been found in variational calculations. The mathematical c3q>ression for this effect k not unique, however. 

Sharma RK, Lemmon M, Bakke J, et al. 1983. Studies of in utero sister chromatid exchange induction and cell replication kinetics [abstract]. Environ Mutagen 5 406. 

Abe S, Nemoto N, Sasaki M. 1983b. Sister-chromatid exchange induction by indirect... 

Tong C, Brat SV, Williams GM. 1981. Sister-chromatid exchange induction by polycyclic aromatic hydrocarbons in an intact cell system of adult rat-liver epithelial cells. Mutat Res 91 467- 473. 

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