Ethoxyacetal

ETHOXYETHANOL (EGEE) and 2-ETHOXYETHYL ACETATE (EGEEA) 2-Ethoxyacetic acid in urine End of shift at end of workweek 100 mg/g creatinine ... 

By allowing phenylmagnesium bromide to react with ethoxyacetal, Spath has shown that the following reaction takes place —... 

Novel isosteres 545 of the antiviral agent acyclovir were synthesized in three stages (84JHC697) by dehydrative coupling of 3-amino-6-aminomethyl[ 1,2,4]triazin-5-(4//)-one with 2-(benzoyloxy)ethoxyacetic acid to give the respective amide that cyclized and deprotected to give 545. It showed no activity against herpes simplex virus types I and II in cell culture (Scheme 112). 

Other difunctional aliphatic carboxylic acids, e.g. lactic add, pyruvic acid, ethoxyacetic acid. 

After treatment of XXXVI with aqueous barium hydroxide, the liquor contained formic, methoxyacetic, and ethoxyacetic acids, methoxyacetone, and ethoxyacetone, produced by the two modes of cleavage XXXVIa and XXXVIb. Formic acid was converted with red mercuric oxide to carbon dioxide this was recovered as barium carbonate, the radioactivity of which was a measure of the C14 incorporated into Cl of kojic acid in the biosynthetic process. The alkoxyacetones were removed from the liquor by steam distillation, and converted to iodoform and a mixture of methoxy- and ethoxy-acetic acids. The iodoform was recovered by filtration its radioactivity indicated the proportion of C14 incorporated into C4. The alkoxy-... 

Because EE is well absorbed through the skin, ambient monitoring of environmental exposure level is not considered to be an accurate method of determining absorbed dose. Biological monitoring of the ethoxyethanol metabolite 2-ethoxyacetic acid in urine has been shown to be an effective indicator of absorbed dose in workers. ... 

Diethoxymethane is the main product obtained at lower temperature (130 °C), whereas methyl ethyl ether, methanol, ethyl propionate and ethoxyacetic derivatives predominate at higher temperature (170 C). Diethylcarbonate, always present among the reaction products, is obtained, however, only in low yields (2-3%). 

When 2-allylbenzofuran (151, Scheme 39) is allowed to react with ethyl (dichloro)ethoxyacetate (152) in the presence of tin(IV) chloride at — 78°C, an electrophilic substitution occurs, and the intermediate 153, after elimination of hydrogen chloride, undergoes an electrocyclic reaction, producing ethyl dibenzofuran-l-carboxylate (154). ... 

C2H6O.CH2.CO(N3) tnw 129.12, N 32.54%, yel pungent oil, causing tears sol in ale, eth, benz expl on heating prepd from ethoxyacetic acid bydrazide and HNO2 Refs 1) Beil 3, (94) 2) T. Curtins, JPrakt-... 

Ethyl glycolic Acid, Ethoxyacetic Acid or Glycolic Ethylether... 

Notes-. Metallic or salt impurities in the sorbent can sometimes cause the irreversible adsorption of electron-rich oxygen functionalities examples include 1-butanol, 2-butanone, and 2-ethoxyacetate recovery rate is often poor for polar compounds... 

Aliphatic alcohols and benzyl alcohol are oxidized by Ph3Bi(OOtBu)2 to the corresponding carbonyl compounds (Equation (141)).233 It has been suggested that the oxidation occurs via dehydrogenation of alcohols by phenyl or tert-butoxy radical. When treated with diethyl ether, Ph3Bi(OOtBu)2 oxidizes the methyl group to afford ethoxyacetic... 

The Step 3 product (14.2 mmol) and ethyl ethoxyacetate (17.75 mmol) were stirred in 80 ml toluene at 0—5°C, then slowly treated with potassium /-buloxidc (15.6 mmol), and then stirred 48 hours at 65°C. The mixture was further treated with 20 ml toluene and 2.4 ml ethyl ethoxy acetate and then stirred an additional 48 hours at 65°C. The solution was then concentrated and triturated with EtOAc to remove unreacted Step 3 reagent. The remaining solid was further triturated with CHC13 and 3.66 g product isolated with an HPLC purity of 80%. 

SYNS ACETIC ACID, ETHOXY- 2-ETHOXYACETIC ACID... 

Ethyl dihydroxyuialonate, 10, S7 Ethylene chlorohydrin, 12,68 14, 28, SS Ethylene cyanohydrin, 16, 88 Ethylene dibromide, 10, 96 Ethyl ethoxyacetate, 13, 42 Ethyl ethyleketeteacarboxylate, 11, 36... 

A large number of symmetrical diaryl- or dialkyl-acetaldehydes, difficult to obtain by other means, have been prepared by the reaction of ethyl ethoxyacetate, or ethyl phenoxyacetate, with Grignard reagents followed by treatment of the resulting glycol monoalkyl ether with anhydrous oxalic acid or dilute sulfuric acid. The yield in the first step is 40-80%, and the yield in the subsequent transformation is 50-80%. 

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