Epithelium growth

A distinctive status of the eye cornea morjrfiology of animals given CMS was epithelization of the whole wound surface. Epithelium growth with immersion into sub-epithelial layer was not observed. Peripheral zones of the wound were covered with a two- to three-layer epithelium wherein a considerable quantity of cells in mitosis was observed. In this zone, collagenic fibers of the cornea itself revealed chemosis, but regulation was observed. Epithelium of adjacent zones comprised four to five layers. In the central sites of the traumatized zone, fibrillogenesis proceeded with higher activity. In contrast to the control and coimective tissue, elements at the wound base contained a few necrotized structures, and much newly formed poorly differentiated connective tissue appeared. 

Inhibition of fibroblastic growth factor (FGF) and epithelium growth factor (EGF),... 

Martinez-Marcos A., Ubeda-Banon I., Deng L. and Halpem M. (2000). Neurogenesis in the vomeronasal epithelium of adult rats evidence for different mechanisms for growth and neuronal turnover. Neurobiology 44, 423-435. 

Miwa T., Moriizumi T., Sakashita H. and Kimura Y. (1993). Transection of the olfactory nerves induces expression of nerve growth factor receptor in mouse olfactory epithelium. Neurosci Lett 155, 96-98. 

Smith T.D., Siegel M.I., Burrows A.M., Mooney M.P., et al. (1999). Histological changes in the fetal human vomeronasal epithelium during volumetric growth of the vomeronasal organ. In Advances in Chemical Signals in Vertebrates (Johnston R.E., Miiller-Schwarze D. and Sorenson P., eds.). Plenum, New York, pp. 583-592. 

Wilson K.C. and Raisman G. (1980). Age-related changes in the neurosensory epithelium of the mouse vomeronasal organ extended period of post-natal growth in size and evidence for rapid cell turnover in the adult. Brain Res 185, 103-113. 

Carcinoma A malignant growth that arises from epithelium, found in skin or the lining of body organs. Carcinomas tend to infiltrate into adjacent tissue and spread to distant organs or a cancerous tumor of the epithelial tissue of an organ. 

Development of a colorectal neoplasm is a multistep process of genetic and phenotypic alterations of normal bowel epithelium structure and function leading to unregulated cell growth, proliferation, and tumor development. 

Although these experiments showed growth was possible using casein hydrolysate, Rose also demonstrated that when the amino acid mixture was used rather than the intact protein, additional calories had to be provided as fat plus carbohydrate, if nitrogen balance was to be maintained. It was later shown that the carbohydrate was needed to protect the free amino acids from oxidation in the intestinal epithelium in the course of absorption. Further, amino acids are poorly tolerated by mouth, causing vomiting and/or diarrhea. After World War II attempts to feed very emaciated prisoners in concentration camps with protein hydrolysates were unsuccessful. It was then recognized that osmotic effects from the amino acids were responsible for the unpleasant consequences. 

However, at the introduction of C60/PVP complex (up to 5 pg/ml) into the cultivating media during cell growth no effects were observed. In the cell MA-104 (cell line derived of green monkey kidney epithelium) grown normally within 3-6 days, no morphological changes and cell metabolism intensiveness were observed (Table 7.1). 

Jacobsen J, van Deurs B, Pedersen M, Rassing MR (1995) TR146 cells grown on filters as a model for human buccal epithelium I. Morphology, growth, barrier properties, and permeability. Int J Pharm 125 165-184... 

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