Entity Post-processing

Exact mass filter exclusion based on the decimal places of a parent dmg, is a post processing filter which allows complete removal of unexpected entities (ions) which do not agree with the criteria preset by the user. Such a filter is fully adjustable once the samples have been processed. This process can dramatically reduce the number of ions in the analyte sample by filtering out the vast majority of matrix-related ions. This will also allow use of very low threshold values to detect low-level metabolites without having to go through the very tedious and long task of manual exclusion of false positives. Typically, extracted ion chromatogram windows of 0.1 mDa allow the... 

The Data Path Allocation tool (EMUCS) determines the number of registers, functional units, and interconnections needed to implement the behavior and assigns appropriate behavioral entities to them. A post-processing phase determines the bussing structure. 

High-pressure liquid chromatography method development of pharmaceuticals is an iterative process required to support successive phases of pharmaceutical development and clinical studies. This chapter details the approach currently in use in our laboratories, from receipt of a new chemical entity to post transfer support. 

While proteins are synthesized on ribosomes the translation product is often subject to considerable post-translational modification that can involve proteolytic processing of the initial proprotein and covalent modification of the processed protein by glycosylation (addition of sugar residues), acylation (e.g. with fatty acids), methylation and phosphorylation. Unconjugated proteins are those in which there is no non-amino acid substituent and conjugated proteins are those that have been modified with non-amino acid entities. 

Due to the unique biosynthetic production process and molecular characteristics of biotechnological and biological products, the DS can include several molecular entities or variants. When these molecular entities are derived from anticipated post-translational modification, they are part of the desired product. When variants of the desired product are formed during the manufacturing process and/or storage and have properties comparable with the desired product, they are considered product-related substances and not impurities. 

The biosynthetic production process and the resulting product may include several molecular entities or variants originating from post-translational modifications in case of proteins and peptides. These are obtained from recombinant or non-recom-binant cell cultures, and are considered to be part of the product. Individual and possibly collective acceptance criteria must be defined which may take into account mea-... 

In El Salvador, most of the poor population felt that aid was being diverted to the richer sections of society and abetted by the people in power at the time. There was the need to create a new entity that would permit coordination between the different groups. Despite efforts to keep the process neutral, the opposition managed to convince voters that their party played a key role in aid distribution and thus won the elections held soon after. The ex post facto analysis may as well have concluded that some of the humanitarian principles were violated, even though aid dehvery itself was acceptable. 

For post-consumer materials, including plastics, the most difficult part of the recychng process may be getting the material collected in the first place. Industrial scrap is owned by the industrial entity that produced it. If the owners cannot get the scrap recycled, they will either have to dispose of it or pay some other business to do so. For much consumer scrap, there is little or no monetary incentive for its owner, the individual consumer, to direct it into a recycling system. Furthermore, industrial scrap tends to be concentrated, with... 

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