Enhancer binding proteins

Similarly, the CCAAT/enhancer-binding protein beta (C/EBPP) can also form homo- and heterodimers with different other factors. 

Morinaga, T., Yasuda, H., Hashimoto, T Higashio, K., and Tamaoki, T. (1991). A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers. Mol. Cell. Biol. 11 6041-6049. 

He G, Margolis DM (2002) Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HlV-1) by the HlV-1 repressor YYl and HlV-1 activator Tat. Mol Cell Biol 22 2965-2973 Henderson AJ, Calame KL (1997) CCAAT/enhancer binding protein (C/EBP) sites are required for HlV-1 replication in primary macrophages but not CD4-t T cells. Proc Natl Acad Sci USA 94 8714-8719... 

Lee ES, Sarma D, Zhou H, Henderson AJ (2002) CCAAT/enhancer binding proteins are not required for HIV-1 entry but regulate proviral transcription by recruiting coactivators to the long-terminal repeat in monocytic cells. Virology 299 20-31... 

Omichinski, J. G., Clore, G. M., Appella, E., Sakaguchi, K., and Gronenborn, A. M. (1990). High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution. Biochemistry 29, 9324-9334. 

Neutrophil-Specific Granule Deficiency. In this rare disorder, secondary or specific granules in neutrophils are absent. The defect may arise from a mutation that leads to the loss of function of the transcription factor CCAAT/enhancer binding protein e (C/EBPe), which is needed for neutrophil response to inflammation (91). Specific granule deficiency affecfs fhe migration of neutrophils. 

Lekstrom-Himes, J. A., and Xanfiiopoulos, K. G., CCAAT/enhancer binding protein s is critical for effective neutrophil-mediated response to inflammatory challenge. Blood 93, 3096-3105 (1999). 

Fig. 1.39. Examples for families of interacting transcription factors. The circles indicate groups of eucaryotic transcription factors that can form homo- and heterodimers amongst themselves. The intersection of the circle of the ATT family with the circle of the Jun family indicates possible heterodimerization between the two famihes. The members of the Jun family can form complexes with members of the Fos family and with the members of the ATT family. The Fos family is unique in that its members can not form homodimers, but must heterodimerize with members of the Jun family. C/EBP CCAAT/enhancer binding protein ATF activating transcription factor CRE-BP cAMP responsive element binding protein. After Lamb and McKnight (1992).

Kustu, S., A. K. North, and D. S. Weiss, Prokaryotic transcriptional enhancers and enhancer-binding proteins. Trends Biochem. Sci. 16 397-401, 1991. First discovered in eukaryotes, enhancers have now been found to exist for a number of prokaryotic genes. 

Kim Y, Fischer SM. 1998. Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues. J Biol Chem 273 27686-27694. 

Magasanik, B. (1988). Reversible phosphorylation of an enhancer binding protein regulates the transcription of bacterial nitrogen utilisation genes. Trends in Biochemical Sciences 13, 475-9. 

Miyakawa, H., S.K. Woo, S.C. Dahl, J.S. Handler, and H.M. Kwon (1999). Tonicity-responsive enhancer binding protein, a novel Rel-like protein that stimulates transcription in response to hyper-... 

Figure 7.42. Model for regulation of AFP synthesis in winter flounder (Pleuronectes americanus). CNS central nervous system GHRH growth hormone releasing hormone GH growth hormone IGF-1 insulin-like growth factor-1 C/EBPa CCAAT enhancer binding protein a AEP antifreeze enhancerbinding protein. See text for details. Arrows with striped tails denote up-regulation or down-regulation.

Ko, B.C. et al., 2002, Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicity-responsive enhancer-binding protein (OREBP/TonEBP). J. Biol. Chem. 277(48) 46085-46092. 

CCAAT box/ enhancer binding protein complement C3 fragment d complement C4 fragment d cornu ammonis... 

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