Endoplasmic reticulum-associated

Boedallo, j. and D. H. Wole, A RING-H2 finger motif is essential For the function of Der3/Hrdl in endoplasmic reticulum associated protein degradation in the yeast Saccharomyces cerevisiae. FEBS Lett, 1999, 448(2-3), 244-8. 

McCracken, A. A. and Brodsky, J. L. Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD). Bioessays 2003, 25, 868—77. 

Ponting, C. P., Proteins of the endoplasmic-reticulum-associated degradation pathway domain detection and function prediction, Biochem. J., 2000, 351 Pt 2, 527. 

The Ubiquitin-Proteasome Pathway and Endoplasmic Reticulum-Associated Degradation... 

Dtirr G, Strajde J, Plemper R, Elbs S, Klee SK, Catty P, Wolf DH, Rudolph HK (1998) The medial-Golgi ion pump Pmrl supplies the yeast secretory pathway with Ca2-f- and Mn2+ required for glycosylation, sorting, and endoplasmic reticulum-associated protein degradation. Mol Biol Cell 9 1149-1162... 

Werner ED, Brodsky JL, McCracken AA (1996) Proteasome-dependent endoplasmic reticulum-associated protein degradation an unconventional route to a familiar fate. Proc Natl Acad Sd USA 93 13797-13801 Wesche J, Rapak A, Olsnes S (1999) Dependence of ridn toxicity on translocation of the toxin A-chain fi om the endoplasmic reticulum to the cytosol. J Biol Chem 274 34443-34449... 

Cross AJ, Crow TJ, Johnson JA, Dawson JM, Peters TJ (1985) Loss of endoplasmic reticulum-associated enzymes in affected brain regions in Huntington s disease and Alzheimer-type dementia. J Neurol Sci 71 137-143. 

ERAD Endoplasmic reticulum-associated protein degradation... 

R. G., Role of A-linked polymannose oligosaccharides in targeting glycoproteins for endoplasmic reticulum-associated degradation. Cell. Mol. Life Sci. 61,1025-1041, 2004 Bedard, K., Szabo, E., Michalak, M., and Opas, M., Cellular functions of endoplasmic reticulum chaperones calreticulin, calnexin, andERp57, Int. Rev. Cytol. 245, 91-121, 2005 Ito, Y, Hagihara,... 

Associated Protein synthesis. See Werner, E.D., Brodsky, J.L., and McCracken, A.A., Proteasome-Degradation dependent endoplasmic reticulum-associated protein degradation an... 

Yamaski, S., Yagishita, N Tsuchimochi, K Nishioka, K., and Nakajima, T, Rheumatoid arthritis as a hyper-endoplasmic reticulum-associated degradation disease, Arthritis Res. Ther. 7, 181-186, 2005 Meusser, B., Hirsch, C Jarosch, E and Sommer, T., ERAD the long road to destruction. Nature Cell Biol. 7, 766-772, 2005. 

Bar-Nun, S. (2005)The role of p97/Cdc48p in endoplasmic reticulum-associated degradation from the immune system to yeast. Curr. Top. Microbiol. Immunol. 300, 95-125. 

Jarosch, E., Lenk, U. and Sommer, T. (2003) Endoplasmic reticulum-associated protein degradation. Int. Rev. Cytol.22i, 39-81. 

Vij N, Fang S, Zeitlin PL. Selective inhibition of endoplasmic reticulum-associated degradation rescues DeltaF508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels therapeutic implications. J. Biol. Chem. 2006 281 17369-17378. 

Nogo, named by Martin Schwab of Zurich University, is a member of the endoplasmic reticulum associated protein family, reticulon. Despite being associated with endoplasmic reticulum of oligodendrocytes, Nogo-A is also exhibited on the surface and mediates growth cone collapse (Fournier et al., 2002). 

Teter, K. and Holmes, R.K. (2002) Inhibition of endoplasmic reticulum-associated degradation in CHO cells resistant to cholera toxin. Pseudomonas aeruginosa exotoxin A, and ricin. Infect Immun, 70, 6172-6179. 

Hazes B and Read RJ (1997). Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells. Biochemistry, 36, 11051-11054. 

Abbreviations CBE conduritol B-epoxide CSF cerebrospinal fluide CMT chaperon-mediated therapy CNS central nervous system ER endoplasmic reticulum ERAD endoplasmic reticulum associated degradation ERT ... 

To complete an understanding of the structural basis of resistance, biophysical studies will be required. A structure for a mammalian endoplasmic reticulum associated CYP has been achieved through expression of a soluble derivative and its crystallization . So far no reports of using... 

Meier, P.J., Spycher, M.A. Meyer, U.A. (1981) Biochim. Biophys. Acta, 646, 293 297. Isolation and characterization of rough endoplasmic reticulum associated with mitochondria from normal rat liver. 

Embden-Meyerhof-Parnas pathway 650 photobioreactors 589,628 endoplasmic reticulum (ER) 648, 701 endoplasmic reticulum associated degradation (ERAD) 701 enzymes 677,703... 

Bordallo J, Plemper RK, Finger A, Wolf DH (1998) De3p/Hrdlp is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins. Mol Biol Cell 9 209-222... 

Wilhovsky S, Gardner R, Hampton R (2000) HRD gene dependence of endoplasmic reticulum-associated degradation. Mol Biol Cell 11 1697-1708... 

Whether oxidants affect the lipase action or promote the synthesis and release of TG-rich lipoproteins has not been determined. It is also possible that TG containing peroxidized fatty acid components are resistant to lipolysis. Earlier studies have demonstrated that antioxidants enhanced the (hepatic) lipase actions [66] however, these studies have not been corroborated or confirmed by more robust studies. In contrast, phospholipases seem to act more robustly on peroxidized or oxidatively tailored phospholipids [67-70] although the enzyme itself could be inactivated by oxidants [70], Recently it was reported that the protein disulfide isomerase, a redox-sensitive enzyme, could contribute to the endoplasmic reticulum-associated degradation of apoB through its chaperone activity [71],... 

Sarah G., Guo, L., Fisher, E.A., and Brodsky, J.L. Protein disulfide isomerases contribute differentially to the endoplasmic reticulum-associated degradation of apolipoprotein B and other substrates Mol. Biol. Cell. 2012 23(4) 520-532. 

Remmer H, Merker HJ (1963) Drug-induced changes in the liver endoplasmic reticulum association with drug-metabolizing enzymes. Science 142 1657-1658... 

In rat spinal ganglia both neuronal and endothehal (the latter predominantly in the smooth endoplasmic reticulum associated with the mitochondria) nitric oxide synthases were localised by their immunoreactivities (Henrich et al. 2001). In vi-bratome slices of rat spinal gangha hypoxia (1 % Oj) stimulated nitric oxide formation while the production of reactive oxygen species was not increased. 

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