Endoplasmic reticulum-associated degradation

McCracken, A. A. and Brodsky, J. L. Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD). Bioessays 2003, 25, 868—77. 

Ponting, C. P., Proteins of the endoplasmic-reticulum-associated degradation pathway domain detection and function prediction, Biochem. J., 2000, 351 Pt 2, 527. 

The Ubiquitin-Proteasome Pathway and Endoplasmic Reticulum-Associated Degradation... 

R. G., Role of A-linked polymannose oligosaccharides in targeting glycoproteins for endoplasmic reticulum-associated degradation. Cell. Mol. Life Sci. 61,1025-1041, 2004 Bedard, K., Szabo, E., Michalak, M., and Opas, M., Cellular functions of endoplasmic reticulum chaperones calreticulin, calnexin, andERp57, Int. Rev. Cytol. 245, 91-121, 2005 Ito, Y, Hagihara,... 

Yamaski, S., Yagishita, N Tsuchimochi, K Nishioka, K., and Nakajima, T, Rheumatoid arthritis as a hyper-endoplasmic reticulum-associated degradation disease, Arthritis Res. Ther. 7, 181-186, 2005 Meusser, B., Hirsch, C Jarosch, E and Sommer, T., ERAD the long road to destruction. Nature Cell Biol. 7, 766-772, 2005. 

Bar-Nun, S. (2005)The role of p97/Cdc48p in endoplasmic reticulum-associated degradation from the immune system to yeast. Curr. Top. Microbiol. Immunol. 300, 95-125. 

Vij N, Fang S, Zeitlin PL. Selective inhibition of endoplasmic reticulum-associated degradation rescues DeltaF508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels therapeutic implications. J. Biol. Chem. 2006 281 17369-17378. 

Teter, K. and Holmes, R.K. (2002) Inhibition of endoplasmic reticulum-associated degradation in CHO cells resistant to cholera toxin. Pseudomonas aeruginosa exotoxin A, and ricin. Infect Immun, 70, 6172-6179. 

Abbreviations CBE conduritol B-epoxide CSF cerebrospinal fluide CMT chaperon-mediated therapy CNS central nervous system ER endoplasmic reticulum ERAD endoplasmic reticulum associated degradation ERT ... 

Embden-Meyerhof-Parnas pathway 650 photobioreactors 589,628 endoplasmic reticulum (ER) 648, 701 endoplasmic reticulum associated degradation (ERAD) 701 enzymes 677,703... 

Bordallo J, Plemper RK, Finger A, Wolf DH (1998) De3p/Hrdlp is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins. Mol Biol Cell 9 209-222... 

Wilhovsky S, Gardner R, Hampton R (2000) HRD gene dependence of endoplasmic reticulum-associated degradation. Mol Biol Cell 11 1697-1708... 

Whether oxidants affect the lipase action or promote the synthesis and release of TG-rich lipoproteins has not been determined. It is also possible that TG containing peroxidized fatty acid components are resistant to lipolysis. Earlier studies have demonstrated that antioxidants enhanced the (hepatic) lipase actions [66] however, these studies have not been corroborated or confirmed by more robust studies. In contrast, phospholipases seem to act more robustly on peroxidized or oxidatively tailored phospholipids [67-70] although the enzyme itself could be inactivated by oxidants [70], Recently it was reported that the protein disulfide isomerase, a redox-sensitive enzyme, could contribute to the endoplasmic reticulum-associated degradation of apoB through its chaperone activity [71],... 

Sarah G., Guo, L., Fisher, E.A., and Brodsky, J.L. Protein disulfide isomerases contribute differentially to the endoplasmic reticulum-associated degradation of apolipoprotein B and other substrates Mol. Biol. Cell. 2012 23(4) 520-532. 

Di Cola A., Frigerio L., Lord J.M., Roberts L.M., and Ceriotti A. 2005. Endoplasmic reticulum-associated degradation of ricin A chain has unique and plant-specific features. PI Physiol 137 287-296. 

Vembar SS, Brodsky JL. (2008) One step at a time endoplasmic reticulum-associated degradation. Nat Rev Mol an Biol 9, 944-957. 

Endoplasmic reticulum, endoplasmic reticulum-associated degradation, and the unfolded protein response... 

Weihl CC, Dalai S, Pestronk A, Hanson PI. (2006) Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation. Hum Mol Genet 15(2), 189-199. 

AlzayadyKJ, PanningMM, Kelley GG, Wojcikiewicz RJ. (2005) Involvement of the p97-Ufdl-Npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4, 5-trisphosphate receptors. J Biol chem 280(41), 34530-34537. 

Zhong X, Shen Y, Ballar P et al. (2004) AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation. JB/a/Cfem 279(44), 45676-45684. 

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