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Adenosine endogenous

Cotter R, Williams C, Ryan L et al (2002) FractaUdne (CX3CL1) and brain inflammation impU-cations for HIV-l-associated dementia. J Neurovirol 8 585-598 Cunha-Reis D, Ribeiro JA, Sebastiao AM (2008) Al and A2A receptor activation by endogenous adenosine is required for VIP enhancement of K+-evoked [3H]-GABA release from rat hippocampal nerve terminals. Neurosci Lett 430 207-212 Davalos D, Grutzendler J, Yang G et al (2005) ATP mediates rapid microglial response to local brain injury in vivo. Nat Neurosci 8 752-758... [Pg.313]

Geiger JD, Parkinson FE, Kowaluk EA. Regulators of endogenous adenosine levels as therapeutic agents. In Jacobson KA, Jarvis MF, eds. Purinergic Approaches in Experimental Therapeutics. New York Wiley-... [Pg.248]

Pak, M. A., Haas, H. L., Decking, U. K. Schrader, J. (1994). Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices. Neuropharmacology 33 (9), 1049-53. [Pg.358]

Mitchell J. B., Lupica C. R., Dunwiddie T. V. (1993). Activity-dependent release of endogenous adenosine modulates synaptic responses in the rat hippocampus. [Pg.457]

Hasko G, Linden J, Cronstein B, Pacher P (2008) Adenosine receptors therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 7 759-770 Hentschel S, Lewerenz A, Nieber K (2003) Activation of A3 receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurones. Res Neurol Neurosd 21 55-63... [Pg.25]

In addition to the activation of the A3 AR by orthosteric agonists that are competitive with adenosine, allosteric enhancers of the action of adenosine and synthetic agonists at the A3AR have been identified. The allosteric modulation of the A3AR in vivo would depend on the release of endogenous adenosine in response to tissue or organ stress. Thus, it would amplify a natural protective response to a challenge. [Pg.98]

The variable effects of NBTI in the immature and mature hippocampus might be ascribed to changes in the levels of endogenous adenosine (Park et al. 1987) and/or in the proportion of A1 and A3AR. [Pg.171]

In conclusion, the excitatory effects of A3AR activation on synchronous epileptiform discharges in vitro suggest that an increase of endogenous adenosine in conditions of stress, that is seizures or hypoxia, may enhance synaptic activity in the immature brain. In addition, they raise the possibility that the A3AR subtype may play a role in the establishment of activity-dependent plastic changes. [Pg.171]

Etherington LA, Frenguelli BG (2004) Endogenous adenosine modulates epileptiform activity in rat hippocampus in a receptor subtype-dependent manner. Eur J Neurosci 19(9) 2539-2550 Fedorova IM, Jacobson MA, Basile A, Jacobson KA (2003) Behavioral characterization of mice lacking the A3 adenosine receptor sensitivity to hypoxic neurodegeneration. Cell Mol Neurobiol 23(3) 431-447... [Pg.183]

Lee KS, Schubert P, Heinemann U (1984) The anticonvulsive action of adenosine a postsynaptic, dendritic action by a possible endogenous anticonvulsant. Brain Res 321(1) 160—164 Lee KS, Lowenkopf T (1993) Endogenous adenosine delays the onset of hypoxic depolarization in the rat hippocampus in vitro via an action at Al receptors. Brain Res 609(1-2) 313-315 Lee JY, Jhun BS, Oh YT, Lee JH, Choe W, Baik HH, Ha J, Yoon KS, Kim SS, Kang I (2006) Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha... [Pg.184]

Gan XT, Rajapurohitam V, Haist JV, Chidiac P, Cook MA, Karmazyn M (2005) Inhibition of phenylephrine-induced cardiomyocyte hypertrophy by activation of multiple adenosine receptor subtypes. J Pharmacol Exp Ther 312(1) 27—34 Gardner NM, Yates L, Broadley KJ (2004) Effects of endogenous adenosine and adenosine receptor agonists on hypoxia-induced myocardial stunning in guinea-pig atria and papillary muscles. J Cardiovasc Pharmacol 43(3) 358-368... [Pg.202]

Correia-de-Sd P, Adaes S, Timdteo MA et al (2006) Fine-tuning modulation of myenteric motoneurons by endogenous adenosine on the role of secreted adenosine deaminase. Auton Neurosci 126-127 211-24... [Pg.363]

Feuerstein TJ, Hertting G, Jackisch R (1985) Modulation of hippocampal serotonin (5-HT) release by endogenous adenosine. Eur J Pharmacol 107 233 42 Filippov AK, Simon J, Barnard EA et al (2003) Coupling of the nucleotide P2Y4 receptor to neuronal ion channels. Br J Pharmacol 138 400-6 Filippov AK, Fernandez-Femandez JM, Marsh SJ et al (2004) Activation and inhibition of neuronal G protein-gated inwardly rectifying K+ channels by P2Y nucleotide receptors. Mol Pharmacol 66 468-77... [Pg.364]

Glass M, Faull RL, Dragunow M (1996) Localisation of the adenosine uptake site in the human brain a comparison with the distribution of adenosine Ai receptors. Brain Res 710 79-91 Go natives J, Queiroz G (1993) Facilitatory and inhibitory modulation by endogenous adenosine of noradrenaline release in the epididymal portion of rat vas deferens. Naunyn-Schmiedeberg s Arch Pharmacol 348 367-71... [Pg.365]

Gubitz AK, Widdowson L, Kurokawa M et al (1996) Dual signalling by the adenosine A2a receptor involves activation of both N- and P-type calcium channels by different G proteins and protein kinases in the same striatal nerve terminals. J Neurochem 67 374-81 Haas HL, Greene RW (1988) Endogenous adenosine inhibits hippocampal CA1 neurones further evidence from extra- and intracellular recording. Naunyn Schmiedeberg s Arch Pharmacol 1988 337 561-5... [Pg.365]

Ribeiro JA, Sebastiao AM (1985) On the type of receptor involved in the inhibitory action of adenosine at the neuromuscular junction.Br J Pharmacol 84 911-18 Ribeiro JA, Sebastiao AM (1986) Adenosine receptors and calcium basis for proposing a third (A3) adenosine receptor. Prog Neurobiol 26 179-209 Ribeiro JA, Sebastiao AM (1987) On the role, inactivation and origin of endogenous adenosine at the frog neuromuscular junction. J Physiol (Lond) 384 571-85... [Pg.369]

Sebastiao AM, Ribeiro JA (1985) Enhancement of transmission at the frog neuromuscular junction by adenosine deaminase evidence for an inhibitory role of endogenous adenosine on neuromuscular transmission. Neurosci Lett 62 267-70... [Pg.370]

Fredholm, BB, Are methylxanthine effects due to antagonism of endogenous adenosine Trends Pharmacol Sci., 1982,1 129-132. [Pg.118]

R. Schulz, J. Rose, H. Post and G. Heusch, Involvement of endogenous adenosine in ischaemic preconditioning in swine, Pflogers Arch 430, 273-282 (1995). [Pg.141]

Begg M, Dale N, Llaudet E, Molleman A, Parsons ME (2002) Modulation of the release of endogenous adenosine by cannabinoids in the myenteric plexus-longitudinal muscle preparation of the guinea-pig ileum. Br J Pharmacol 137 1298-1304... [Pg.357]

Do KQ, Vollenweider FX, Zollinger M, Cuenod M (1990) Effect of climbing fibre deprivation on the K -evoked release of endogenous adenosine from rat cerebellar slices. Eur. J. Neurosci, 3, 201. [Pg.325]

Kmmp E, Picard S, Mancini J, Borgeat P Suppression of leukotriene B4 biosynthesis by endogenous adenosine in ligand-activated human neutrophils. J Exp Med 1997 186 1401-1406. [Pg.138]

See other pages where Adenosine endogenous is mentioned: [Pg.20]    [Pg.443]    [Pg.50]    [Pg.169]    [Pg.171]    [Pg.172]    [Pg.175]    [Pg.177]    [Pg.191]    [Pg.195]    [Pg.204]    [Pg.226]    [Pg.345]    [Pg.348]    [Pg.364]    [Pg.366]    [Pg.71]    [Pg.20]    [Pg.268]    [Pg.507]    [Pg.5]    [Pg.285]    [Pg.184]    [Pg.287]    [Pg.62]    [Pg.518]   
See also in sourсe #XX -- [ Pg.348 ]



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