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The initial interest in utilizing TNF as a general anti-cancer agent has diminished, largely due to the realization that [Pg.250]

Cancer Cachexia Stimulation of growth of some tumours [Pg.251]

Septic shock Vascular leakage Tissue necrosis H5 potension Activates blood clotting [Pg.251]

Rheumatoid arthritis Tissue inflammation Possible role in destruction of joints [Pg.251]

Diabetes Death of pancreatic islet cells induces insulin resistance [Pg.251]

See other pages where TNF therapeutic aspects is mentioned: [Pg.250]

TNF