Electrolyte lavage solution

The values given above pertain to solution on reconstitution of one flavor pack. When dissolved in sufficient water to make 4 L, the final solution contains 125 mEq/L sodium, 10 mEq/L potassium, 20 mEq/L bicarbonate, 80 mEq/L sulfate, 35 mEq/L chloride, and 18 mEq/L polyethylene glycol 3350. The reconstituted solution is isos-motic and has a mild, salty taste. Colyte Flavor Packs are available in citrus berry, lemon lime, cherry, and pineapple. This preparation can be used without the Colyte Flavor Packs and is administered orally or via a nasogastric tube. Each Citrus Berry Flavor Pack (3.22 g) contains hydroxypropyl methylcellulose 2910, citrus berry powder, 

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Whole-bowel irrigation with polyethylene glycol-electrolyte lavage solution has become popular for colon cleansing before diagnostic procedures or colorectal operations. 

Brady CE 3rd, DiPalma JA, Morawski SG, Santa Ana CA, Fordtran JS. Urinary excretion of polyethylene glycol 3350 and sulfate after gut lavage with a polyethylene glycol electrolyte lavage solution. Gastroenterology 1986 90(6) 1914-18. 

Anonymous. PEG electrolyte lavage solutions drug evaluation monograph. Englewood (CO) Micromedex Inc, 1999 1-21. 

PEG-ELS polyethylene glycol-electrolyte lavage solution PHM peptide histidine methionine VIP vasoactive intestinal peptide... 

Several studies have evaluated the effect of these two bowel preparations on the amount of residual fluid present within the colon at the time of CTC. The standard PEG solution usually leaves a large quantity of residual fluid within the colon that may hamper visibility for the radiologist, but it poses no problems to the endoscopist, since fluid maybe easily aspirated by the endoscope. Radiologists prefer a dry colon, such as that produced by phospho-soda and/or magnesium citrate, as this generally results in a smaller amount of residual fluid compared to the electrolyte lavage solutions (Macari et al. 2001). Furthermore, patients usually tolerate saline cathartics better than they do PEG (Kolts et al. 1993 Oliveira et al. 1997). 

Polyethylene glycol electrolyte lavage solution is often the agent preferred by gastroenterologists for colonic cleansing in patients prior to fiberoptic colonoscopy. One unit of the solution is composed of 236 g of polyethylene glycol as well as electrolytes such as sodium and potassium and is administered orally in a large volume to empty the colon. 

Sharma VK, Chockalingham SK, Ugheoke EA, Kapur A, Ling PH, Vasudevaa R, Howden CW (1998) Prospective, randomized, controlled comparison of the use of polyethylene glycol electrolyte lavage solution in four-liter versus two-liter volmnes and pretreatment with either magnesium... 

Despite the large amount of published studies on CTC, there is no consensus about the optimum regimen for bowel preparation. Two commonly used bowel-deansing regimens are polyethylene glycol electrolyte (PEG) lavage solution and saline cathartics such as phospho-soda and magnesium citrate, both of which are available in commercial preparations. Table 17.1 details the most common preparation schemes. 

Preoperative mechanical bowel preparation polyethylene glycol-electrolyte solution lavage - 4 liters p.o. over 3-4 h starting at 6.00 a.m. on the day prior to surgery sodium phosphate1 prep of 45 ml p.o. at 6.00 p.m. 2 days prior to surgery and 6.00 a.m. the day prior to surgery... 

Apart from specific antidotes (if they exist), the treatment of poisonings also calls for symptomatic measures (control of blood pressure and blood electrolytes monitoring of cardiac and respiratory function prevention of toxin absorption by activated charcoal). An important step is early emptying of the stomach by gastric lavage and, if necessary, administration of an osmotic laxative. Use of emetics (saturated NaCl solution, ipecac syrup, apomorphine s.c.) is inadvisable. 

Oral electrolyte solutions for colonic lavage before colonoscopy or barium enema. Med Lett Drugs Ther 1985 27 39 0. 

D. Colorectal Preoperative lavage recommended, Go-Lytely electrolyte solution (4 liters) Preoperative day... 

Gastric lavage should be carried out immediately if oral consumption is suspected. In order to hasten intestinal elimination charcoal tablets should be administered at 4-hr intervals with sodium sulfate as laxative. To activate the antimony the chelating agent Sulfactin must be administered intramuscularly and also about every 4 hr. Chelated antimony is excreted renally and is readily dialyzed. Hence continuous hemodialysis can be carried out if necessary. The administration of Sulfactin must be continued throughout the whole dialysis. The intravenous administration of lasix with a balanced substitution of electrolyte solutions to force diuresis is also promising in cases of very high levels of Sb intoxication [33]. 

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