Polyethylene glycol-electrolyte preparations

Docusate salts Bisacodyl Polyethylene glycol-electrolyte preparations... 

Preoperative mechanical bowel preparation polyethylene glycol-electrolyte solution lavage - 4 liters p.o. over 3-4 h starting at 6.00 a.m. on the day prior to surgery sodium phosphate1 prep of 45 ml p.o. at 6.00 p.m. 2 days prior to surgery and 6.00 a.m. the day prior to surgery... 

Miettinen RP, Laitinen ST, Markela JT, Paak-konen ME Bowel preparation with oral polyethylene glycol electrolyte solution vs. no preparation in elective open colorectal surgery Prospective, randomized study. Dis Colon Rectum 2000 43 669-675. 

Magnesium salts, e.g. magnesium sulphate (Epsom salt), sodium phosphates, and polyethylene glycol-electrolyte solutions, produce largely fluid stools, and are useful in pre-operative preparation of the bowel. 

Preparation of bowel for procedure Polyethylene glycol/electrolytes (Golytely) - 4 1 p.o. once... 

Irrigation with large volumes of a polyethylene glycol-electrolyte solution, e.g. Klean-Prep, by mouth causes minimal fluid and electrolyte disturbance (it was developed for preparation for colonoscopy). Magnesium sulphate may also be used. 

Despite the large amount of published studies on CTC, there is no consensus about the optimum regimen for bowel preparation. Two commonly used bowel-deansing regimens are polyethylene glycol electrolyte (PEG) lavage solution and saline cathartics such as phospho-soda and magnesium citrate, both of which are available in commercial preparations. Table 17.1 details the most common preparation schemes. 

Fluid redistributes between prone and supine imaging (Fig. 14.19). Polyethylene glycol electrolyte solution bowel preparation typically results in more retained colonic fluid, compared to other bowel preparation regimens, but leaves less particulate stool matter in the colon. Fluid can also be seen in 3D endoluminal images (Fig. 14.20). When there is excessive fluid, intravenous contrast can be used to enhance submerged lesions. 

Polyethylene glycol-electrolyte solution (PEG) is routinely prescribed for bowel cleansing, but often poorly tolerated by patients. Sodium phosphate (NaP) may be an alternative. Patients who previously xmderwent colonoscopy were invited to participate in the study and were randomly assigned to PEG or NaP. The endoscopist filled out a report about preparation, tolerability and future preferences. A total of 125 patients were included in the study, 7 of whom were excluded because of missing data. The remaining 116 (53 PEG and 63 NaP) patients were included in the analysis [51 ]. 

Van Vugt A, Van Pinxteren MWJ, Van Kouwen MCA, Van Oijen MGH, Van Achterberg T, Nagengast FM. A prospective study of bowel preparation for colonoscopy with polyethylene glycol-electrolyte solution versus sodium phosphate in Lynch syndrome a randomized trial. Fam Cancer 2012 11(3) 337-41. 

High doses of salt laxatives are used for bowel preparation for diagnostic and surgical procedures. Also used for bowel preparation is polyethylene glycol (PEG) with electrolytes, commonly referred to as Colyte or GoLYTELY. PEG is administered in amounts of 3 to 4 liters over 3 hours. Patients may be advised to keep GoLYTELY refrigerated to make it more palatable. PEG is an isotonic, nonabsorbable osmotic substance that contains sodium salts. Therefore, patients with renal impairment or cardiac disorder can use potassium chloride. 

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