Electrochemical medical biosensors nanomaterials

The use of carbon-based nanomaterials such as CNTs and graphene for the development of POC biosensors has attracted attention due to their physical, electrical, electrochemical, and chemical properties. In particular, one-dimensional nanostructures are very attractive for designing high-density arrays for ultrasensitive protein detection due to their high surface-to-volume ratio and electron-transport properties. Such nanostructures represent a promise for the development of multiple biomaikers assays in ultrasmall sample volumes, being of special interest for medical areas. ... 

Table 12.1 Nanomaterial-modified electrochemical biosensors for medical applications... 

Kerman, K., Saito, M., Tamiya, E., Yamamura, S., Takamura, Y., 2008. Nanomaterial-based electrochemical biosensors for medical apphcations. Trends in Analytical Chemistry 27, 585-592. 

Nanostructured electrode arrays and nanomaterial-based labeling strategies have resulted in ultrasensitive devices for measuring clinically relevant biomolecules. Due to their small size, electrocatalytic properties, compatibility with microfluidics, and ability to be functionalized with biomolecules, nanomaterial-derived electrochemical biosensor arrays have shown promise in applications that require the simultaneous detection of multiple biomolecules. As personalized medicine and future medical diagnostics require the development of small, sensitive, versatile, low-cost, and energy-efficient devices for multiplexed detection of biomolecules from complex samples, nanomaterial-based bioelectrochemistry is poised to address the rigorous demands of biosensor development. 

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