Medical biosensors

In addition to conventional applications in conducting polymers and electrooptical devices, a number of recent novel applications have emerged. Switching of DNA electron transfer upon single-strand/double-strand hybridization fonns the basis for a new medical biosensor teclmology. Since the number of base pairs of length 20... 

Medical biosensors for point of care (POC) applications Edited by R. J. Narayan... 

Medical Biosensors for Point of Care (POC) Applications. http //dx.doi.org/10.1016/B978-0-08-100072-4.00001-0 Copyright 2017 Elsevier Ltd. All rights reserved. 

DNAzymes are another class of nucleic acid probes that have been widely used in medical biosensors because of their ability to catalyticaUy cut specific substrate when a designated cofactor is introduced. DNAzymes were discovered by Breaker and Joyce in 1994 who found that in the presence of Pb + a particular single-strand (ss)DNA strand could catalyze transesterification reactions since then, various reports have been made discovering that DNAzymes catalyze cleavage, ligation, and phosphorylation of nucleic acids. DNAzymes are beneficial because of their ease of synthesis and stability compared to their RNA and protein counterparts. ... 

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