Efficacy of disinfectants

Method for assessing the efficacy of disinfectants by the modified ChickMartin test BS 808 1986 [1991]. 

As already mentioned, smooth, polished surfaces are cleaned most easily. Floors and horizontal surfaces should be cleaned and disinfected daily, walls and ceilings as often as required, but the interval should not exceed 1 month. Regular microbiological monitoring should be carried out to determine the efficacy of disinfection procedures. Records should be kept and immediate remedial action taken should normal levels for that area be exceeded. 

Whitehead, K. and McCue, K. A. (2010). Virucidal efficacy of disinfectant actives against feline calicivirus, a surrogate for norovirus, in a short contact time. Am. J. Infect. Control 38, 26-30. 

Methods used to study the efficacy of disinfection methods... 

Hellstrom, S., Kervinen, R., Lyly, M., Ahvenainen-Rantala, R., and Korkeala, H. (2006). Efficacy of disinfectants to reduce Listeria monocytogenes on precut iceberg lettuce. J. Food Prot. 69,1565-1570. 

Oit, R.V. and Beuchat, L.R (2000) Efficacy of disinfectants in killing spores of Alicyclohacillus acidoterrestris and performance of media for supporting colony development by survivors. Journal of Food Protection 63(8), 1117-22. 

The effectiveness and frequency of the disinfection procedure shall be determined as part of the process validation. Evaluation of the efficacy of disinfectants should be related to the reduction of types and numbers of micro-organisms recovered from surfaces during routine environmental monitoring. 

D Michel, GA Zach. Antiseptic efficacy of disinfecting solutions in suspension test in vitro against methiciUin-resistant Staphylococcus aureus. Pseudomonas aeruginosa and Escherichia coli in pressure sore wounds after spinal cord injury. Dermatology 195 (suppl 12) 36-41, 1997. 

B Terleckyj, DA Axler. Efficacy of disinfectants against fungi isolated from skin and nail infections. J Am Podiatr Med Assoc 83(7) 386-393, 1993. 

British Standard 808, Method for Assessing the Efficacy of Disinfectants by the modified Chick-Martin test, 1986. 

These authors have suggested that glutaraldehyde- and succinal-dehyde-based products are the only disinfectants suitable for the decontamination of endoscopes [272], although a recent report proposes the use of 0.5% phthalaldehyde, which achieves a 5-log reduction in bacterial load, does not require dilution and does not emit irritating vapours as with other aldehydes [296]. Alternative agents have also been proposed in experiments designed to evaluate the efficacy of disinfection of bronchoscopes contaminated with M. tuberculosis or MAI [297]. 

Bessems, E., 1998. The effect of practical conditions on the efficacy of disinfectants. International Biodeterioration and Biodegradation 41, 177-183. 

Takeo, Y., Oie, S., Kamiya, A., Konishi, H. and Nakazawa, T., 1994. Efficacy of disinfectants against biofilm cells of Pseudomonas aeruginosa. Microbios 79, 19-26. 

Koch discovered the methods to evaluate the antimicrobial efficacy of disinfectants. 

The efficacy of disinfectants is affected by various factors, such as the target microorganisms, the environment of the microorganisms, the contaminated object, the microbicidal ingredients, and the mode of application. Three of these five factors - the microorganisms, the environment, and the object - are given by the disinfection task. The other two factors - the microbidde, the mode of application - depend on the disinfection method itself (Spicher, 1996). 

Testing the efficacy of disinfectants is influenced by a variety of factors, such as the target organisms, the environment of the mieroorganisms, the contaminated object, the microbicidal ingredients, and the mode of... 

E1837-96. Standard test method to determine efficacy of disinfection processes for reusable medical devices (simulated use test). 

Several methods have been developed to test the efficacy of disinfecting formulas (antiseptic formulas will not be treated here). Whatever the active ingredient may be, formulas claiming disinfectancy must be tested for their efficacy at recommended use concentrations. 

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