Ecklonia cava

McKey D (1974) Adaptive patterns in alkaloid physiology. Am Nat 108 305-320 Molis M, Korner J, Ko YW, Kim JH, Wahl M (2006) Inducible responses in the brown seaweed Ecklonia cava the role of grazer identity and season. J Ecol 94 243-249 Moore BS (2006) Biosynthesis of marine natural products macroorganisms (Part B). Nat Prod Rep 23 615-629... 

Heo, S. J., Park, P. J., Park, E. J., Kim, S. K., and Jeon, Y. J. 2005b. Antioxidant activity of enzymatic extracts from a brown seaweed Ecklonia cava by electron spin resonance spectrometry and comet assay. Ear. Food Res. Technol., 221,41-41. 

Examples of other anti-HIV compounds also included four phlorotannin derivatives, eckol, 8,8 -dieckoI, 8,4 -dieckoI and phlorofucofiiro-eckol A, isolated from the brown alga Ecklonia cava [65]. Among these compounds, 8,8 -dieckol and 8,4 -dieckol exhibited an inhibitory effect on HIV-1 RT and protease. An enzyme kinetic assay... 

Diammo nium glycyrrhizi nate Ecklonia cava Emblica officinalis Epigallocatechin- 3 -gallate Erigeron annuus Caffeic acid Erythrina senegalensis Evodiae fructus Evodiamine Ferula assafoetida Flavonoids Forsythia suspensa... 

The brown algae Ecklonia cava is known for its antioxidant and anti-inflammatory functions. The butanol extract of E. cava reduces Ap secretion from HEK293 cells expressing APP with Swedish mutation and increases soluble APPa and C-terminal fragment-a (CTFa), of which activity is similar to BACE (P-site of APP cleaving enzyme) inhibitors. The extract inhibits Ap oligomerization, particularly midsize oligomer formation, and protects primary cortical neurons from various Ap-induced cell deaths [210]. 

Kang IJ, Jeon YE, Yin XF, Nam JS, You SG, Hong MS et al (2011) Butanol extract of Ecklonia cava prevents production and aggregation of beta-amyloid, and reduces beta-amyloid mediated neuronal death. Food Chem Toxicol 49 2252-2259... 

Protective effect of triphlorethol-A from Ecklonia cava against ionizing radiation in vitro. J Radiat Res (Tokyo) 47, 61-8. 

Ahn M J, Yoon K D, Min S Y, et al. (2004). Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava. Biol. Pharm. Bull. 27 544-547. 

Heo, S., Ko, S., Cha, S., Kang, D., Park, H., Choi, Y., Kim, D., Jung, W., and Jeon, Y. (2009a). Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation. Toxicol. In Vitro 23, 1123-1130. 

Kong, C. S., Kim, J. A., Yoon, N. Y., and Kim, S. K. (2009). Induction of apoptosis by phlorogludnol derivative from Ecklonia Cava in MCF-7 human breast cancer cells. 

Yoon, N., Eom, T., Kim, M., and Kim, S. (2009). Inhibitory effect of phlorotaimins isolated from Ecklonia cava on mushroom tyrosinase activity and melanin formation in mouse B16F10 melanoma cells. /. Agric. Food Chem. 57,4124-4129. 

Lee, H., Kang, C., Jung, E. S., Kim, J. S., and Kim, E. (2011). Antimetastatic activity of polyphenol-rich extract of Ecklonia cava through the inhibition of the Akt pathway in A549 human lung cancer cells. Food Chem. 127,1229-1236. 

FIGURE 123 Possible anticoagulation mechanism of fucoidan from brown seaweed Ecklonia cava. 

Athukorala, Y., Jung, W. K., Vasanthan, T., and Jeon, Y. J. (2006). An anticoagulative polysaccharide from an enzymatic hydrolysate of Ecklonia cava. Carbohydr. Polym. 66, 184 191. 

Shim, S. Y., Le, Q. T., Lee, S. H., and Kim, S. K. (2009b). Ecklonia cava extract suppresses the high-affinity IgE receptor, FceRI expression. Food Chem. Toxicol. 47, 555-560. 

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