Drug delivery vehicles, characterization

Djordjevic, L., Primorac, M., Stupar, M. and Krajisnik, D. (2004) Characterization of capry-locaproyl macrogolglycerides based microemulsion drug delivery vehicles for an Amphiphilic drug. Int. J. Pharm., 271, 11-19. 

Djordjevic L, Primorac M, Stupar M, Krajisnik D. Characterization of caprylocaproyl macrogolglyc-erides based microemulsion drug delivery vehicles for an amphiphilic drug. International Journal of Pharmaceutics. 2004 271(1) 11-19. 

Rehman K, Mohd Amin MCI, Zulfakar MH. Development and physical characterization of polymer-fish oil bigel (hydtogel/oleogel) system as a transdermal drug delivery vehicle. Journal ofOleo Science. 2014 63(10) 961-970. 

No. 10, May 2002, p.2167-77 CHARACTERIZATION OF BIODEGRADABLE DRUG DELIVERY VEHICLES WITH THE ADHESIVE PROPERTIES OF LEUKOCYTES... 

Phospholipid molecules form bilayer films or membranes about 5 nm in thickness as illustrated in Fig. XV-10. Vesicles or liposomes are closed bilayer shells in the 100-1000-nm size range formed on sonication of bilayer forming amphiphiles. Vesicles find use as controlled release and delivery vehicles in cosmetic lotions, agrochemicals, and, potentially, drugs. The advances in cryoelec-tron microscopy (see Section VIII-2A) in recent years have aided their characterization [70-72]. Additional light and x-ray scattering measurements reveal bilayer thickness and phase transitions [70, 71]. Differential thermal analysis... 

Applications of cationic dendrimers as transport vehicles have been described, with an emphasis on their use as transfection agents for nucleic acids. They can transfect them into a large number of cell lines and primary culture cells.Dendrimers with protonable amine groups can interact with all forms of nucleic acid by electrostatic interactions to form complexes that condense the nucleic acids. Whereas linear polymers often adopt random coil structures, the 3D structure of a dendrimer is characterized by radial symmetry. To solve many cellular obstacles of gene delivery, functionalization and variation of the dendrimer structure is an important tool that can be applied. These systems have shown stability and non-immunogenic properties for their potential use in a high variety of therapeutic applications and have been successfully used as carriers for nucleic acids and drug delivery. ... 

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