Drug coated medical device

Medical Applications. Virtually all biomedical and bioengineering research projects make use of microscopy at some point. Scientists in the pharmaceutical industry, for example, need to closely examine the physical structure and dispersion characteristics of the active components (chemicals) used in the development of drugs, as well as the materials used to coat medical devices such as pacemakers or other implants. Eluorescence microscopy and confocal microscopy are commonly used for these purposes. 

A1 Lamee K and Cook D. Polymer coating techniques for drug eluting stent. Medical device technology 2003 http /www.medicalde vicesonline.com/ mdt/articledetail.j se =52234. 

Stimuli-responsive polymers have gained increasing interest and served in a vast number of medical and/or pharmaceutical applications such as implants, medical devices or controlled drug delivery systems, enzyme immobilization, immune-diagnosis, sensors, sutures, adhesives, adsorbents, coatings, contact lenses, renal dialyzers, concentration and extraction of metals, for enhanced oil recovery, and other specialized systems (Chen and Hsu 1997 Chen et al. 1997 Wu and Zhou 1997 Yuk et al. 1997 Bayhan and Tuncel 1998 Tuncel 1999 Tuncel and Ozdemir 2000 Hoffman 2002 en and Sari 2005 Fong et al. 2009). Some novel applications in the biomedical field using stimuli-responsive materials in bulk or just at the surface are shape-memory (i.e., devices that can adapt shape to facilitate the implantation and recover their conformation within the body to... 

The reaction is allowed to proceed at 178°C for some 4 h. After completition of the reaction, the bioabsorbable polymer is extruded and allowed to cool for a minimum of 16 h. The resulting bioabsorbable terpolymer contains about 40% Pluronic F68, 51% of caprolactoyl groups, 9% of glycoyl groups, and less than 1% of residual caprolactone monomer (29). The resulting composition may be utilized to form medical devices, drug delivery devices, or coatings for other medical devices. 

---