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Drotrecogin

Drotrecogin alfa may be utilized for patients at a high risk of mortality, and is not utilized for patients at a low risk of mortality (as defined by APACHE II scores). [Pg.1185]

Patients predicted to follow a severe course require treatment of any cardiovascular, respiratory, renal, and metabolic complications. Aggressive fluid resuscitation is essential to correct intravascular volume depletion and maintain blood pressure. IV colloids may be required because fluid losses are rich in protein. Drotrecogin alfa may benefit patients with pancreatitis and systemic inflammatory response syndrome. IV potassium, calcium, and magnesium are used to correct deficiency states. Insulin is used to treat hyperglycemia. Patients with necrotizing pancreatitis may require antibiotics and surgical intervention. [Pg.320]

Drotrecogin is effective in patients at high risk of death (Acute Physiology and B... [Pg.503]

Administration of activated protein C (drotrecogin) to promote fibrinolysis and associated antiinflammatory mechanisms may be beneficial in patients with an APACHE II (Acute Physiology and Chronic Health Evaluation II) score greater than 25. This agent reduced mortality in severe sepsis but poses an increased risk of serious bleeding. [Pg.505]

Drotrecogin a (activated) - recombinant human Reducing mortality in patients with severe... [Pg.60]

Cilostazol (Pletal) Drotrecogin Alfa (Xigris) Eculizumab (Soliris) Lanthanum Carbonate (Fosrenol)... [Pg.57]

Xigris (Drotrecogin-a rh activated protein C, produced in a Eli Lilly Severe sepsis 2001 (USA), 2002 (EU)... [Pg.507]

A. General description Drotrecogin alfa (activated) is a recombinant form of human Activated Protein C. An established... [Pg.267]

Dosage form Xigris is supplied as a sterile, lyophilized powder in vials containing 5 and 20 mg drotrecogin aha (activated) and excipients. [Pg.268]

Drotrecogin alfa (acitvated), human recominant of activated protein C... [Pg.452]

Adjunctive immunomodulatory drugs such as drotrecogin-alfa can also be considered for patients with severe sepsis. [Pg.1104]

See other pages where Drotrecogin is mentioned: [Pg.110]    [Pg.442]    [Pg.1491]    [Pg.70]    [Pg.1194]    [Pg.1195]    [Pg.1195]    [Pg.1195]    [Pg.587]    [Pg.345]    [Pg.503]    [Pg.588]    [Pg.143]    [Pg.172]    [Pg.408]    [Pg.409]    [Pg.409]    [Pg.462]    [Pg.267]    [Pg.268]    [Pg.268]    [Pg.452]    [Pg.500]    [Pg.555]    [Pg.331]    [Pg.143]    [Pg.172]    [Pg.19]   
See also in sourсe #XX -- [ Pg.19 ]



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Drotrecogin alfa

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Drotrecogin alfa Heparin

Drotrecogin-alpha

Sepsis, drotrecogin alfa

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