Dopamine receptors genes

Spitz, M.R., Shi, H., Yang, F. et al. Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients [see comment], J. Natl. Cancer Inst. 90 358, 1998. 

Meador-Woodruff J., Little K., Damask S., Mansour P., Watson S. Effects of cocaine on dopamine receptor gene expression A study in the postmortem human brain. Biol. Psychiatry. 34 348, 1993. 

Noble EP et al. D2 dopamine receptor gene and cigarette smoking a reward gene Med Hypotheses 1994 42(4) 257-260. 

Thompson J et al. D2 dopamine receptor gene (DRD2) Taql A polymorphism reduced dopamine D2 receptor binding in the human striatum associated with the Al allele. Pharmacogenetics 1997 7(6) 479-484. 

Accili, D., Fishburn, C. S., Drago, J. etal. A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice. Proc. Natl Acad. Sci. U.S.A. 93 1945-1949,1996. 

Caveats aside, the five dopamine receptors remain candidates in disease. The pharmacological properties that have been used to group them into dopamine Dj-like and dopamine D -like receptors may also be useful to consider when surveying the dopamine receptor gene association studies. For the most part, the D -like dopamine receptors Dj (50-52) and Dj (53) have not been as widely associated with disease as the D dopamine receptors. The D -like receptors D (54), D3 (55), and D (56) have similar dopamine sensitivities and are much more polymorphic than the Dj-like receptors (49,57). 

Strobel, A., Lesch, K. P., Hohenberger, K., et al. (2002) No association between dopamine receptor gene exon III and -521C/T polymorphism and novelty seeking. Mol. Psychiatry. 7, 537-538. 

Lerer, B., Segman, R. H., Fangerau, H., et al. (2002) Pharmacogenetics of tardive dyskinesia combined analysis of 780 patients supports association with dopamine receptor gene Ser9Gly polymorphism. Neuropsychopharmacology. 27, 105-119. 

Dikeos, D. G., Papadimitiiou, G. N., Avramopoulos, D., et al. (1999) Association between the dopamine receptor gene locus (DRD3) and unipolar affective disorder. Psychiatr. Genet. 9, 189-195. 

Wu X, Hudmon KS, Detry MA, et al (2000) D2 dopamine receptor gene polymorphisms among African-Americans and Mexican-Americans a lung cancer case-control study. Cancer Epidemiol Biomarkers Prev 9 1021-1026... 

Bruins-Slot, L., Gorwood, P., Bouvard, M., Blot, P., Ades, J., Fein-gold, J., Schwartz, J.C., Mouren, S., and Marie, C. (1998) Lack of association between anorexia nervosa and D3 dopamine receptor gene. Biol Psychiatry 43 76-78. 

Jensen S, Plaetke R, Holik J, et al Linkage analysis of the Dj dopamine receptor gene and manic depression in six families. Hum Hered 42 269-275, 1992 Jeste DV, Eastham JH, Lacro JP, et al Management of late-life psychosis. J Clin Psychiatry 57 [suppl 3) 39-45, 1996... 

Benjamin, Joathon, Lin Li, Chavis Patterson, Benjamin D. Greenberg, Dennis L. Murphy, and Dean H. Hamer. 1996. "Population and Familial Association Between the D4 Dopamine Receptor Gene and Measures of Novelty Seeking." Nature Genetics 12 81-84. 

Blum, Kenneth, Peter J. Sheridan, R. C. Wood, Eric R. Braverman, T. J. Chen, John G. Cull, and David E. Comings. 1996b. "The D2 Dopamine Receptor Gene as a Determinant of Reward Deficiency Syndrome." Journal of the Royal Society of Medicine 89 396-400. 

Noble, Ernest P. 1993. "The D2 Dopamine Receptor Gene A Review of Association Studies in Alcoholism." Behavior Genetics 23 119-29. 

Noble, Ernest P., Kenneth Blum, M. E. Khalsa, Terry Ritchie, Anne Montgomery, R. C. Wood, R. J. Fitch, T. Ozkaragoz, Peter J. Sheridan, M. D. Anglin, A. Paredes, L. J. Treiman, and R. S. Sparks. 1993. "Allelic Association of the D2 Dopamine Receptor Gene with Cocaine Dependence." Drug and Alcohol Dependence 33 271-85. 

Noble, Ernest P., S. T. St. Jeor, Terry Ritchie, K. Syndulko, S- C. St. Jeor, R. J. Fitch, R. L. Brunner, and R. S. Sparkes. 1994. "D2 Dopamine Receptor Gene and Cigarette Smoking A Reward Gene " Medical Hypotheses 4 257-60. 

Meador-Woodruff JH, Davis KL, Haroutunian V. 2001. Abnormal kainate receptor expression in prefrontal cortex in schizophrenia. Neuropsychopharmacology 24 545-552. Meador-Woodruff JH, Grandy DK, Van Tol HH, Damask SP, Little KY, et al. 1994. Dopamine receptor gene expression in the human medial temporal lobe. Neuropsychopharmacology 10 239-248. 

Grandy DK, Zhang Y, Bouvier C, Zhou QY, Johnson RA, Allen L, Buck K, Bunzow JR, Salon J, Civelli O (1991) Multiple human D5 dopamine receptor genes a functional receptor and two pseudogenes. Proc Natl AcadSci USA 88 9175-9179. 

Le Moine C, Bloch B (1995) D1 and D2 dopamine receptor gene expression in the rat striatum sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct neuronal populations of the dorsal and ventral striatum. J Comp Neurol 355 418 126. 

Le Moine C, Tison F, Bloch B (1990a) D2 dopamine receptor gene expression by cholinergic neurons in the rat striatum. Neurosci Lett 777 248-252. 

Le Moine C, Normand E, Guitteny AF, Fouque B, Teoule R, Bloch B (1990b) Dopamine receptor gene expression by enkephalin neurons in rat forebrain. Proc Natl Acad Sci USA 57 230-234. 

Grandy DK, Zhou QY, Allen L, Litt R, Magenis RE, Civelli O, Litt M (1990) A human D1 dopamine receptor gene is located on chromosome 5 at q35.1 and identifies an EcoRI RFLP. Am J Hum Genet 47 828-834. 

Cadoret M-A, Jaber M, Bloch B (1993) Prenatal D1( D1B and D3 dopamine receptor gene expression in the rat forebrain detection by reverse polymerase chain reaction. Neurosci Lett 755 92-95. 

Pohjalainen T, Rinne JO, Nagren K, Lehikoinen P, Anttila K, Syvalahti EK, Hietala J (1998) The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers. Mol Psychiatry 3 256—260. 

Noble, E.P. Addiction and its reward process through polymorphisms of the D2 dopamine receptor gene a review. Eur. Psychiatry 2000, 15, 79-89. 

Makoff AJ, Graham JM, Arranz MJ, Forsyth J, Li T, Aitchison KJ, Shaikh S, Grunewald RA. Association study of dopamine receptor gene polymorphisms with drug-induced hallucinations in patients with idiopathic Parkinson s disease. Pharmacogenetics 2000 10(l) 43-8. 

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