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Disinfectants sporicidal activity

A number of aldehydes possess antimicrobial properties, including sporicidal activity however, only two, formaldehyde and glutaraldehyde, are used for disinfection. Both these aldehydes are highly effective biocides and their use as chemosterilants reflect this. [Pg.214]

Formaldehyde is available as a 40% w/v solution in water (100% formalin). An 8% formaldehyde solution in water has a broad spectrum of activity against bacteria, fungi, and viruses. Sporicidal activity may take as long as 18 hours. Its rapidity of action is increased by solution in 70% isopropanol. Formaldehyde solutions are used for high-level disinfection of hemodialyzers, preparation of vaccines, and preservation and embalming of tissues. The 4% formaldehyde (10%... [Pg.1163]

The experimental disinfectant solutions tested exhibited significant sporicidal activity against B. subtilis spores. The B. subtilis strain used in these evaluations is the same one specified in the AO AC sporicidal test. Spores from... [Pg.8]

The acridine dyes, acriflavine and aminacrine, have also been employed for skin disinfection and treatment of infected wounds or burns. They are slow acting and mainly bacteriostatic in effect, with no useful fungicidal or sporicidal activity. Acriflavine is a mixture of two components, proflavine and euflavine. Only euflavine has effective antimicrobial properties. [Pg.303]

Iodophors are complexes of iodine with a surface-active agent such as polyvinyl pyrrolidone (PVP povidone-iodine). Iodophors retain the activity of iodine. They kill vegetative bacteria, mycobacteria, fungi, and lipid-containing viruses. They may be sporicidal upon prolonged exposure. Iodophors can be used as antiseptics or disinfectants, the latter containing more iodine. The amount of free iodine is low, but it is released as the solution is diluted. An iodophor solution must be diluted according to the manufacturer s directions to obtain full activity. [Pg.1096]

Phenols (Fig. 17.7) are widely used as disinfectants and preservatives. They have good antimicrobial activity and are rapidly bactericidal but generally are not sporicidal. Their activity is markedly diminished by dilution and is also reduced by organic matter. They are more active at acid pH. The main disadvantages of phenols are their caustic effect on skin and tissues and their systemic toxicity. The... [Pg.300]


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See also in sourсe #XX -- [ Pg.241 ]




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