Diseases of the nervous system

Keeler MH and Reifler CB (1967). Grand mal convulsions subsequent to marijuana use. Diseases of the Nervous System, 18, 474-475. 

Giulian, D. Microglia and diseases of the nervous system. Curr. Neurol. 12 23-27,1992. 

Clinical pain is characterized by the presence of spontaneous pain or hypersensitivity to pain-provoking stimuli. Hypersensitivity includes pain produced by low-intensity stimuli that normally only elicit an innocuous sensation (allodynia), or an exaggerated response to a noxious stimulus (hyperalgesia). There are two distinct forms of clinical pain, the pain that occurs after tissue injury or inflammatory diseases (inflammatory pain) and the pain associated with a lesion or disease of the nervous system (neuropathic pain). Although the mechanisms responsible for the initiation and maintenance of these pains differ, they are both characterized by heightened... 

Because of its antiviral and anticancer effects, IFN-a is used in the treatment of hepatitis and various forms of cancer, such as Kaposi s sarcoma, non-Hodgkin s lymphoma, and hairy cell leukemia. Exhibit 4.8 describes the treatment of hepatitis C with IFN- . IFN-jS is used for treating multiple sclerosis, a chronic disease of the nervous system. The medical application of IFN-y is for cancer, AIDS, and leprosy. 

Inpus erythematosus A chronic inflammatory disease of connective tissue, affecting the skin and internal organs, lymphoma A malignant tumor of the lymph nodes, multiple sclerosis A disease of the nervous system, myelodysplasia Abnormal or defective formation of the bone marrow. Mycoplasma Minute primitive bacteria without a rigid cell wall. Mycoplasma pneumoniae causes atypical pneumonia in humans, myeloma cells Malignant tumor cells. 

Diseases of the Nervous System Linked to the Ubiquitin-Proteasome Pathway 739... 

This pretty much sums up the key features of the nervous system of humans and identifies some of the key molecules involved one way or another with its functions. In the next chapter, I turn attention largely to diseases of the nervous system but conclude with a vignette about the mechanisms for learning and memory. 

Fishman RA, Cerebrospinal Fluid in Diseases of the Nervous System, W.B. Saunders Company, Philadelphia, 1980. 

Parkinson s disease A degenerative disease of the nervous system characterized hy tremor and impaired muscular coordination, patient-directed designer drug A dmg developed to meet the medical needs of very specific fypes of individuals, pharmacopoeia A catalog of drugs, chemicals, and medicinal preparations. 

The powdered seeds of Mucuna pruriens L. have been used in Ayurvedic medicine for diseases of the nervous system and have shown to reduce adverse effects in PD patients. HP-200, a commercial extract of M. pruriens was shown to be twice as effective as the equivalent dose of L-DOPA in rats, although a later study showed that when the same preparation was given to rats over a 52 weeks period, it did not elevate DA levels in the striatum nigrum, but in the cortex. This calls into question whether the observed improvements in parkinsonian symptoms were due to the hypothesis originally proposed i.e. that the L-DOPA in the Mucuna extract was converted to DA and reached the parts of the brain where a deficiency is associated with PD. ... 

Parkinson s disease—Disease of the nervous system caused by failure to make a particular signal molecule patients have muscle weakness and shaking of arms and legs. 

N Central nervous system (CNS) 290-319 320-359 Mental and behavioral disorders Diseases of the nervous system... 

In Taiwan the ratio of deaths occurring above age 65 of total deaths for a category varied widely. In 1985 the ratio ranged from 33% for diseases of the nervous system to 70% for diseases of the respiratory system. In 2002 the corresponding ratios for these two categories increased... 

Kupfer DJ, Himmelhoch JM, Schwartzberg M, et al Hypersomnia in manic-depressive disease. Diseases of the Nervous System 33 720-724, 1972... 

Bender, L. "D-lysergic Acid in the Treatment of the Biological Feature of Childhood Schizophrenia," Diseases of the Nervous System, Monograph Supplement 27, 43-46,1966. 

Mistletoe leaves are given in hysteria, epilepsy, chorea and other diseases of the nervous system. As an anti-spasmodic and tonic it is used in cardiac dropsy. 

Choi, D. W. (1988). Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634. Choi, D. W. (1990). Methods for antagonizing glutamate neurotoxicity. Cerebrovasc. BrainMetab. Rev. 2, 105-147. 

Section II Gene Therapy with Virus Vectors for Specific Disease of the Nervous System... 

Hornykiewicz, 0. "Handbook of Clinical Neurology, Vol. 29, Metabolic and Deficiency Diseases of the Nervous System" Vinken, P.J. Bruyn, G.W., Eds. North Holland Amsterdam, 1977 pp. 459-483. 

It was Louis Lewin, of Phantastica fame, who first suggested that banister-ine might be useful in the treatment of diseases of the nervous system. And it was Kurt Beringer, of der Meskalinrausch fame, who ran the first clinical study using banisterine on 15 patients with postencephalitic parkinsonism, in 1928. Other studies reinforced the virtues of this drug. Initially, doses of 20 or 40 mg were... 

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