Directions for Use

Labeling. Labeling, controUed by FDA regulations, includes not only the affixed labels, but also the package inserts that provide mote detailed information. Trade, generic, or common name, dose, number of dose units present, and name and address of manufacturer and distributor ate requited. For nonptescription products, adequate directions for use ate requited. Prescription products must beat the phrase, "Caution Federal law prohibits use without a prescription" on theit labels. 

Magnesium anodes are usually built into the object to be protected through isolating sockets or holes (see Fig. 20-6) and joined to them with cables. They must be readily accessible and easily exchangeable for convenient control [4]. The directions for use have to indicate the necessity for an inspection after 2 years of operation. During operation, control can be exercised by electrical measurements (current, resistance). In addition, acoustic and optical methods exist to determine the amount of anode consumption [4]. The life of the anodes is usually more than 5 years (see Section 6.6). 

Gebrauchs-anweisung, /. directions for use. -dosis, /. usual dose. 

Figure 9-124B. Directions for using Figure 9-124A. Used by permission of Westinghouse Electric Corp., Sturtevant Div.

The directions for use of translingual nitroglycerin are supplied witii die product. Follow the instructions regarding using and cleaning the canister. 

Follow die directions on die label or use as directed by die primary healdi care provider. Read any enclosed directions for use of the product carefully. 

In hospitals today a wide variety of complex equipment is used in the course of patient treatment. Humidifiers, incubators, ventilators, resuscitators and other apparatus require proper maintenance and decontamination after use. Chemical disinfectants used for this purpose have in the past through misuse become contaminated with opportunist pathogens, such as Ps. aeruginosa, and ironically have contributed to, rather than reduced, the spread of cross-infection in hospital patients. Disinfectants should only be used for their intended purpose and directions for use must be followed at all times. 

OPPTS 860.1000 Background OPPTS 860.1100 Chemical Identity OPPTS 860.1200 Directions for Use OPPTS 860.1300 Nature of Residue - Plants, Livestock OPPTS 860.1340 Residue Analytical Method OPPTS 860.1360 Multiresidue Method OPPTS 860.1380 Storage Stability Data OPPTS 860.1400 Water, Fish, Irrigated Crops OPPTS 860.1460 Food Handling OPPTS 860.1480 Meat/Milk/Poultry/Eggs OPPTS 860.1500 Crop Field Trials OPPTS 860.1520 Processed Food/Feed OPPTS 860.1550 Proposed Tolerances... 

Containers of insecticides and other economic poisons must bear labels showing the name or brand of the article, the net contents, the name and address of the manufacturer or distributor, an ingredient declaration, an appropriate warning or caution statement, including the word POISON (in red), the skull and crossbones, and an antidote statement on highly toxic materials. Adequate directions for use must accompany each economic poison. Devices subject to the act are not required to bear labels but if they... 

When sufficient information is available concerning a substance to justify releasing it to the general public, labeling containing adequate directions for use and necessary precautionary statements should be prepared and affixed to each package. Users of economic poisons should be educated to follow directions and observe precautions in every instance... 

These major categories are based largely on acute toxicity records, but the significance of chronic poison hazards to the adequacy of warning and directions-for-use labeling is given full consideration whenever it is a factor for public protection. 

Labels should bear adequate directions for use, proper statement of ingredients, and any precautions or warnings necessary for proper use of the product. New chemicals for pest control are not permitted to be sold until data are developed to demonstrate that they can be used in accordance with proper directions without undue hazard. 

Class II recalls are those in which the use of or exposure to a product found in violation of the law may cause a temporary health problem that is reversible, or in which the situation would not cause serious adverse health consequences. Examples of this type of recall would include uncertainty of the sterility of an injectable product, Salmonella contamination of various types of oral dosage forms, inadequate directions for use, and improper buffering of solution for injection [20]. 

The label states (1) the date after which the gel is not intended to be used (2) the conditions under which the gel should be stored (3) the directions for use. 

Aniline black (Cl Oxidation Base 1) is a complex polymeric phenazine that can be produced on cotton fabric by impregnation with aniline hydrochloride and suitable inorganic oxidants, such as sodium chlorate, ammonium vanadate and copper hexacyanoferrate(II). Aniline black is also made directly for use as a pigment (Cl Pigment Black 1). 

It is a legal requirement to affix a prescription label on the immediate container of prescription medications. The pharmacist is responsible for the accuracy of the label. It should bear the name, address, and the telephone number of the pharmacy, the date of dispensing, the prescription number, the prescriber s name, the name and address of the patient, and the directions for use of the medication. Some states require additional information. The name and strength of the medication, and the refill directions are also written frequently. The label for a sample prescription is in Figure 3.2. 

Abbreviations—Includes symbols and acronyms used in drug names as well as directions for use. 

In the U.S., unlike most nations, some antibiotic products for mastitis therapy are available to the dairyman without a veterinary prescription. For FDA approval of an over-the-counter intramammary infusion product, it is required that adequate directions for use be written so that the layman can use the drug safely and for the purposes for which it is intended. The following antibiotics are currently approved and marketed for intramammary infusion in treatment of bovine mastitis (26) ... 

The United Kingdom Medicines Act 1968 regulations require that all medicinal products are properly labelled to certain minimum standards, but requirements vary from country to country. Clinical trial materials, however, cannot be labelled normally because if the trial is blind, nothing should reveal to the patient or physician the nature of the contents. The basic information on the label should provide the patient s name, study phase, study number, directions for use, any special warning or storage requirements, expiry date and the investigator s name and address, along with an indication that the... 

Directions for use Empty packet contents into a small cup containing 1 to 2 tablespoons of water. Do not use other liquids or foods. Stir well and drink immediately. Refill cup with water and drink. 

A detailed discussion of the above topics together with a selection of class projects and test calculations is given in Chapter 7 of Rowell (1994, pp. 131-152), but note his calculation of CEC has an error in that it is based on 250 ml KCI extract, not on 100 ml as per given methodology, and thus requires correction (confirmed by personal communication, 2001). Directions for using the Eoss/Perstorp Analytical Tecator Kjeltec Auto 1035/1038 Sample System for CEC determinations are given in USDA, 1996 (pp. 203-210). 

It is the purpose of this section to provide the modern vocabulary required for the description of stereoselective reactions. This also implies the description of stereochemical aspects of starting materials and products, i.e., aspects of static stereochemistry. The material has been arranged in logical progression and, whenever possible, rules and directions for use or explicit definitions of important terms are given. 

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