1,2 diphenylethylamine

Irradiation of an equimolar mixture of t-S and DCNB in 9 1 acetonitrile-water solution containing ammonia results in the formation of 1,2-diphenylethylamine in 46% yield106. 

Ph-CH )-CH(NH3)-Me HS04 ] with copper(n) nitrate was more successful in that the (S)-( —)-enantiomer (15) was formed in 85 per cent chemical yield and 95 per cent optical purity.6 (S)-( — )-10,10 -Dihydroxy-9,9 -biphenanthryl has been similarly prepared from the coupling of 9-phenanthrol, using (R)-( —)-1,2-diphenylethylamine and copper(n) nitrate.7 Enantioselective syntheses of... 

Substituted a-nitrostilbenes were hydrogenated to 1,2-diphenylethylamines in 52-87% yields, conveniently in methanol over in situ-prepared Pd-C catalyst (eq. 9.28).53 In these cases the hydrogenation was carried out in presence of the hydrogen chloride formed from palladium chloride, the amount of which, however, was much smaller (-0.0022 mol) for the nitrostilbenes hydrogenated (0.037-0.042 mol). In one instance, a-nitro-4 -methoxystilbene gave rise to a small amount of the corresponding oxime when the hydrogen uptake was less than theoretical. 

Preparative Methods racemic l,l -bi-2,2 -naphthol (BINOL) is most conveniently prepared by the oxidative coupling reaction of 2-naphthol in the presence of transition metal complexes (eq 1). The resolution of racemic BINOL with cinchonine may be performed via the cyclic phosphate (eq 2). An alternative procedure to provide directly optically active BINOL is the oxidative coupling of 2-naphthol catalyzed by Cu salt in the presence of chiral amines (eq 3). The best procedure uses (+)-amphetamine as the chiral ligand and provides BINOL in 98% yield and 96% ee. Above 25 °C the Cu /(+)-amphetamine/(5)-BINOL complex precipitates, while the more soluble Cu /(+)-amphetamine/(I )-BINOL complex is slowly transformed into the former complex. 9,9 -Biphenanthrene-10,10 -diol has also been prepared in 86% yield and with 98% ee by a similar asymmetric oxidative coupling of 9-phenanthrol in the presence of (I )- 1,2-diphenylethylamine. ... 

N-Methyl-1,2-diphenylethylamine AND HYDROCHLORIDE, 34, 64 2-Methyldodecanoic acid, 38, 43, 47, 49 2-Methyl-2-dodecenoic acid, 38, 49,50 trans-2-Methyl-2-dodecenoic acid,... 

Captopril (11) is another ACE inhibitor used for the reduction of blood pressure [34,35]. The traditional approach has to been to resolve 3-acyl-2-methylpropionic acids with 1,2-diphenylethylamine, A-isopropylphenylethanol, dehydroabiety-... 

Low molecular weight reactants such as phthalic anhydride and dimethylsuccinic anhydride were used as model compounds for trimellitic anhydride terminated polystyrene and styrene-maleic anhydride (SMA) copolymer. As amine functional species, benzyl-amine and 1,2 diphenylethylamine, were employed, the transposal of the knowledge gained from model compounds to a real polymer blend system reacted in the melt under shear was only slightly instmctive. The low reactivity observed in the case of the reactive polymers has been ascribed to a chemically different environment and not to a diffusion-controlled process as is generally considered. 

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