Digestive tract absorption

McLachlan, M.S. Digestive tract absorption of polychlorinated diobenzo-p-dioxins, dibenzofurans, and biphenyls in a nursing infant, Toxicol. Appl. Pharmacol., 123, 68, 1993. 

Aspirin To facilitate digestive tract absorption, aspirin is usually combined with metoclopramide. Self-medication is widespread. Its efficacy versus placebo is well documented, generally at the dose of 1 g/d. 

Caffeine is often used in combination with ergotamine tartrate to improve digestive tract absorption. However caffeine has an antimigraine action itself. 

Schlummer M, Moser GA, McLachlan MS. 1998. Digestive tract absorption of PCDD/Fs, PCBs, and HCB in humans Mass balances and mechanistic considerations. Toxicol Appl Pharmacol 152 128-137. 

DHBs are rapidly absorbed through the digestive tract. Their absorption through skin is low in aqueous solution but may be increased in suitable... 

MiCHAELSEN s, OTTE J, SIMONSEN L-0 and SORENSEN H (1994) Absorption and degradation of individual intact glucosinolates in the digestive tract of rodents , Acta Agric. Scand. Sect. A. Animal Sci., 44 25-37. 

Curcumin possesses strong antioxidant capacities, which may explain its effects against degenerative diseases in which oxidative stress plays a major role. As previously described for flavonoids, it is unlikely that curcumin acts as a direct antioxidant outside the digestive tract since its concentration in peripheral blood and organs is very low (near or below 1 pM, even after acute or long-term supplementation). Indeed, it has been shown that the intestinal epithelium limits its entry into the body, as reflected by absorption studies in various models (portal blood perfusion, everted bags). ... 

The gastrointestinal tract (GIT) is a highly specialized region of the body whose primary functions involve the processes of secretion, digestion, and absorption. Since all nutrients needed by the body, with the exception of oxygen, must first be ingested orally, processed by the GIT, and then made available for absorption into the bloodstream, the GIT represents a significant barrier and interface with the environment. The primary defense mechanisms employed by the gut... 

H. W. Davenport, Gastric digestion and emptying Absorption, in Physiology of the Digestive Tract, 3rd Ed., Year Book Medical Publishers, Chicago, 1971, pp. 163-171. 

Mucosa. The innermost layer of the wall is the mucosa, which consists of a mucous membrane, the lamina propria, and the muscularis mucosa. The mucous membrane provides important protective and absorptive functions for the digestive tract. The nature of the epithelial cells lining the tract varies from one region to the next. Rapidly dividing stem cells continually produce new cells to replace worn out epithelial cells. The average life span of these epithelial cells is only a few days. The lamina propria is a thin middle layer of connective tissue. This region contains the capillaries and small lymphatic vessels that take up the digested nutrient molecules. The muscularis mucosa is a thin layer of smooth muscle. Contraction of this muscle may alter the effective surface area for absorption in the lumen. 

CH 4 TRANSPORT INTO THE BODY THE GASTROINTESTINAL TRACT, DIGESTION AND ABSORPTION... 

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