Dichlorodiphenyltrichloroethane pesticides

In a case-control study of pesticide factory workers in Brazil exposed to methyl parathion and formulating solvents, the incidence of chromosomal aberrations in lymphocytes was investigated (De Cassia Stocco et al. 1982). Though dichlorodiphenyltrichloroethane (DDT) was coformulated with methyl parathion, blood DDT levels in the methyl parathion-examined workers and "nonexposed" workers were not significantly different. These workers were presumably exposed to methyl parathion via both inhalation and dermal routes however, a dose level was not reported. The exposed workers showed blood cholinesterase depressions between 50 and 75%. However, the baseline blood cholinesterase levels in nonexposed workers were not reported. No increases in the percentage of lymphocytes with chromosome breaks were found in 15 of these workers who were exposed to methyl parathion from 1 week to up to 7 years as compared with controls. The controls consisted of 13 men who had not been occupationally exposed to any chemical and were of comparable age and socioeconomic level. This study is limited because of concomitant exposure to formulating solvents, the recent history of exposure for the workers was not reported, the selection of the control group was not described adequately, and the sample size was limited. 

Williams, G.M. and S. Numoto. 1984. Promotion of mouse liver neoplasms by the organochlorine pesticides chlordane and heptachlor in comparison to dichlorodiphenyltrichloroethane. Carcinogenesis 5 1689-1696. 

Dichlorodiphenyltrichloroethane, better known as DDT, is a well-known pesticide that has caused significant environmental damage. It is easy to point fingers, blaming scientists and manufacturers for having unleashed this organic compound on an unsuspecting world. It is more difficult, however, to understand why this environmental disaster took place. 

DDT (dichlorodiphenyltrichloroethan e) Pesticide Well above 278 mg/Kg. - None identified EPA identified as of Moderate Toxicity 2000-5000 mg/Kg rat -skin LD50 Will naturally decay to DDE and then stop all further degradation... 

My last example of disproportionate concerns making things worse involves the disease malaria, and the use of the pesticide dichlorodiphenyltrichloroethane commonly known as DDT.14... 

Chlorobenzenes have been widely used as solvents and degreasing agents in pesticides, including dichlorodiphenyltrichloroethane (DDT), and in dielectric fluids as industrial precursors in the production of phenols and as dyestuff intermediates. Chlorobenzenes represent a unique class of compounds because their hydrophobicity increases with chlorine substitution,... 

DDT, the abbreviation for dichlorodiphenyltrichloroethane, is a pesticide once called miraculous by Winston Churchill because of the many lives it saved by killing diseasecarrying mosquitoes. DDT use is now banned in the United States and many developed countries because it is a nonspecific insecticide that persists in the environment. 

See also Aflatoxin Algae Ammonia Asbestos Benzene Hexachloride, Mixed Isomers Brodifacoum Carbamate Pesticides Carbon Monoxide Castor Bean Copper Coumarins DDT (Dichlorodiphenyltrichloroethane) DEET (Diethyltoluamide) Dichlorvos Dieldrin Ethylene Glycol Hydrogen Sulfide Lead Malathion Methane Molybdenum Mushrooms, Coprine Mushrooms, Cyclopeptide Mycotoxins Nitrites Oleander Organochlorine Insecticides Organophosphates Paraquat Parathion Pyrethrins/Pyrethroids Selenium Sodium Strychnine Sulfur Dioxide Thallium Warfarin. 

Pesticides Trimethyl phosphothioate, carbofuran, organochlorines (Aldrin, Dieldrin, Endrin, Chlordane, Heptachlor, Lindane, DDT, i.e., dichlorodiphenyltrichloroethane), organophosphates (Malathion, Parathion) The existing epidemiological studies are inadequate to raise conclusions on the immunotoxic risk associated to pesticide exposure [36]... 

Dichlorodiphenyltrichloroethane (DDT). This is by far the most notorious pesticide ever used,... 

Pesticides as pollutants. By pesticides we mean substances for the suppression and destruction of harmful organisms. Pesticides are used particularly in plant production. Originally, mainly inorganic substances were used. Most of them are also used currently, particularly in the form of salts or oxides. However, advances in organic chemistry led to the industrial production of ever more relatively inexpensive synthetic organic substances characterized by their extraordinary efficiency. The first of these was dichlorodiphenyltrichloroethane (DDT), which became commercially available as an insecticide in 1942. At the present time, organic pesticides are in wide-spread use. 

Figure 1 Chemical structures of (A) polychlorinated biphenyls (PCBs) (B) dichlorodiphenyltrichloroethane (DDT) and the metabolites dichlorophenyidichloroethane (DDD) and DDE (C) other chlorinated pesticides. C, carbon atoms H, hydrogen atom Cl, chlorine atom.

Sites contaminated by chlorinated pesticides (e.g. dichlorodiphenyltrichloroethane (DDT), aldrin, dieldrin, and endrin) and herbicides (e.g. atrazine, molinate and bentazone) due to agricultural activities and accidental spills have received little attention (Chapters 11 and 12). These contaminants are nonpolar in characteristics and sorb strongly to the soil. Similar to other hydrophobic organic compounds, desorption using solubilizing agents such as surfactants and cosolvents as well as... 

As with all chemicals, the dose makes the poison. The chlorine-containing insecticide dichlorodiphenyltrichloroethane (DDT) is highly effective in killing disease-ridden mosquitoes, ticks, and fleas, but it is virtually nontoxic to mammals. The fluorine-containing pesticide 1080, or fluoroacetic add (FCH2CO2H), is highly toxic and often lethal to all mammals. The industrial and combustion by-product dioxin is highly toxic to some animals but not to others in humans, dioxin causes the skin disease chloracne. 

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