Diazolidinyl urea

DIAZOLIDINYL UREA Water soluble Weak anti-yeast activity... 

Diazolidinyl urea, antimicrobial used in cosmetics, 7 831t Diazomethane... 

Plague psoriasis treatment Calcipotriene Dovonex Cetearyl alcohol, Ceteth-20 Diazolidinyl urea, dichlorobenzyl alcohol... 

Preservatives. Most products must contain preservatives to ensure that yeasts, molds, and bacteria do not thrive in them. These preservatives include alcohol, methylparaben, propylparaben, DMDM hydantoin, diazolidinyl urea, and imidazolidinyl urea. The parabens have limited solubility in water, eg, 0.25% for methylparaben and 0.05% for propylparaben (22). If these levels are exceeded in the formula, then the addition of solvents is needed to ensure clear, stable products. 

Aqua, glycerin, cyclomethicone, dicaprylyl carbonate, ascorbic acid, butyrospermum parkii, alcohol cetearyl, octocrylene, glyceryl stearate, C12-15 alkyl-benzoate, cera microcristallina, tocopheryl acetate, vitis vinifera, PEG-40 stearate, sodium carbomer, paraffinum liquid-urn, tetrasodium iminodisucciunate, BHT, phenoxyethanol, methyl paraben, propyl paraben, diazolidinyl urea and parfum. 

Formaldehyde-releasing preservatives, such as quater-nium-15, diazolidinyl urea, and imidazolidinyl urea, are widely used in cosmetics and topical medications and are well-known contact sensitizers. In spite of positive patch test reactions to these preservatives in a number of patients, only some of these patients will react when they use the corresponding commercial formulations. This is because the concentrations of preservatives in the commercial products are often below the threshold necessary to produce a clinical reaction. This finding confirms the importance of using commercial formulations of topical agents in estimating the clinical relevance of patch test results (10). 

Antimicrobial activity similar to imidurea. " Diazolidinyl urea is the most active of the imidazolidinyl family of preservatives. Used in concentrations of 0.1-0.5% w/w, at pH 3-9, it has predominantly antibacterial properties. Typical MICs are Aspergillus niger 4000 pg/mL Candida albicans 8000 pg/mL Escherichia coli 1000 pg/mL Pseudomonas aeruginosa lOOOpg/mL Staphylococcus aureus 250 pg/mL. 

Imidurea is the best known of a family of heterocyclic urea derivatives that are effective antimicrobial preservatives. Diazolidinyl urea has the greatest antimicrobial activity. 

Preservatives can be classified into two types compounds that release formaldehyde and compounds that do not release formaldehyde. Formalin, an aqueous solution of formaldehyde, is a commonly used preservative in shampoos and conditioners [3], Although formaldehyde has been known as a sensitizer, it is not a problem if used at 0.1 % or lower. The use of formaldehyde in baby shampoos is not recommended. Other preservatives that fall in the formaldehyde-releasing group are diazolidinyl urea, imidazolidinyl urea, and DMDM (dimethyloldimethyl) hydantoin. 

H20. Cream contains calcipotriene monohydrate equivalent to 50 pg/g anhydrous calcipotriene in a cream base of cetearyl alcohol, ceteth-20, diazolidinyl urea, dichlo-robenzyl alcohol, dibasic sodium phosphate, edetate disodium, glycerin, mineral oil, petrolatum, and water. 

Propylene glycol, diazolidinyl urea, methylparaben, and propylparaben 10.00... 

The lotion contains pramoxine hydrochloride 1% and zinc acetate 0.1% and inactive ingredients alcohol USP, camphor, citric acid, diazolidinyl urea, fragrance, glycerin, hydroxypropyl methylcellulose, methylparaben, oil of lavender, oil of rosemary, polysorbate 40, propylene glycol, propylparaben, purified water, and sodium citrate. The... 

Germaben . [Sutton Labs] Diazolidinyl urea blends antimicrobi preservative for cosmetic prods. 

Bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)-1,3-bis(hydroxymethyl)urea Diazolidinyl urea EINECS 278-928-2 German 11 Imidazolidinyl urea 11 N-(1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)- N-(1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-N, N -bis-(hydroxymethyl)urea N-(Hydroxymethyl)-N-(1,3-di-hydroxymethyl-2,5 tioxo-4-imidazolidinyl)- N-(Hydro-xymethyl)-N-(1,3-dihydroxymethyl-2,5-dioxo-4-imidazol-idinyl)-N -... 

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