Device controlled delivery

Future Potential of Device Controlled Delivery of Powders 264... 

The high permeability of PCL and its copolymers coupled with a controllable induction period prior to polymer weight loss (vide infra) lends itself to the development of delivery devices that are based on diffusion-controlled delivery of the drug during the induction period prior to weight loss. The subsequent biodegradation of the polymer serves the purpose of eliminating the need to recover the spent device. 

Control elements, final, 20 684-687 Controlled atmosphere storage (CAS), of food products, 12 77 21 564-565 Controlled delivery devices, biocompatibility of, 9 56 Controlled depletion polymer antifouling coatings, 7 158... 

The unique properties of responsive gels have resulted in substantial applications research, especially over the past decade. In general, these applications can be classified as mechanical devices, controlled solute delivery devices, or chemical separation techniques. A recent book edited by DeRossi et al. covers these applications in more detail [71],... 

An IUD is a small medical device that is inserted through the cervix and placed within the uterus. The device may contain a drug-loaded polymeric component allowing the controlled delivery of an active... 

In polymeric membrane and matrix-based micropumps, the membrane or the matrix makes the essential component of the delivery device that controls the rate of release. In matrix controlled delivery, the rate of the hydrolytic breakdown of the matrix is the governing process. In polymeric membrane-controlled release, the rate of hydration of the membrane and the subsequent diffusion of drug are the rate-controlling steps. 

Membrane-reservoir systems based on solution-diffusion mechanism have been utilized in different forms for the controlled delivery of therapeutic agents. These systems including membrane devices, microcapsules, liposomes, and hollow fibres have been applied to a number of areas ranging from birth control, transdermal delivery, to cancer therapy. Various polymeric materials including silicone rubber, ethylene vinylacetate copolymers, polyurethanes, and hydrogels have been employed in the fabrication of such membrane-reservoir systems (13). 

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