Designated confirmer

The wedges used in structure 4.1 and indeed in all similar homoporphyrin structures in this chapter are used to designate confirmed deviation from macrocyclic planarity at this particular position, and should not be taken as an assignment of absolute stereochemistry. In no case has the separation of homoporphyrin enantiomers been reported. However, racemic epimers that result from substitution at this out-of- plane wcso-like position have in some cases been separated, and solid and hashed wedges are used to designate these epimeric forms as appropriate. 

Subassembly Behavior Uata Reduction, Interpretatl and Analysis Design Confirmation... 

It is advisable to obtain some pharmacokinetics data prior to initiating the studies for the study design, confirmation of administration dose and evaluation of test results. 

Chau95 David Chaum Designated Confirmer Signatures Eurociypt 94, LNCS 950, Springer-Verlag, Berlin 1995, 86-91. 

Okam94 Tatsuaki Okamoto Designated confirmer signatures and public-key encryption are equivalent Crypto 94, LNCS 839, Springer-Verlag, Berlin 1994, 61-74. 

Experimental data on hexane emulsification effectiveness in reaction zone of divergent-convergent design confirm calculation results received with the help of the worked out technique (Fig. 3.31) very well. Equations (3.41) and (3.43) are held for values of densities of both continuous and disperse phases in interval 0,689+1111 kg/m. ... 

Design of the two new sulphating roaster lines included testwork on feed samples, performed in Johannesburg, South Africa. Most of the tests were conducted on the concentrate samples, in order to characterize their physical and chemical properties. Furthermore, a limited number of pilot scale runs were conducted, to improve the feed nozzle design, confirm the product s physical and chemical properties, and verify the cobalt and copper recoveries. 

Study (Simpson et al., 1979b) with the same experimental design confirmed that almost exactly the same findings are applicable to type one patients. 

The Institution of Structural Engineer s publication, Aims of structural design confirms that... 

After development of a new process scheme at laboratory scale, constmction and operation of pilot-plant faciUties to confirm scale-up information often require two or three years. An additional two to three years is commonly required for final design, fabrication of special equipment, and constmction of the plant. Thus, projections of raw material costs and availabiUty five to ten years into the future become important in adopting any new process significantly different from the current technology. 

Sohd materials, such as gilsonite and asphalt, and partially soluble sulfonated asphalt may also be added to plug small fractures in exposed shale surfaces and thereby limit water entry into the formation (105,124). The asphalts are oxidized or treated to impart partial solubiUty. These materials may be softened by the downhole temperature, causing them to deform and squeeze into small openings exposed to the borehole. Laboratory tests designed to evaluate shale-stabilizing muds have confirmed the beneficial action of these materials (125) (see also Soil STABILIZATION). 

The most volatile product (myristic acid) is a small fraction of the feed, whereas the least volatile product (oleic—stearic acids) is most of the feed, and the palmitic—oleic acid split has a good relative volatility. The palmitic—oleic acid split therefore is selected by heuristic (4) for the third column. This would also be the separation suggested by heuristic (5). After splitting myristic and palmitic acid, the final distillation sequence is pictured in Figure 1. Detailed simulations of the separation flow sheet confirm that the capital cost of this design is about 7% less than the straightforward direct sequence. 

The objectives of the study should be precisely stated and the work presented in a clear and coherent matter, with all the detail necessary to allow the reviewer to make his or her own assessment of the study. It should be confirmed that the overall design of the protocol satisfies the needs of the objectives of the study. 

In 1990, a third form of soHd carbon was confirmed and designated TuckniinsterfilUetenes. These 60-carbon (and 78-C) clusters are described as having the shape of a geodesic dome or soccer ball and hence are also known as "bucky balls" (5). 

These results indicate that is it possible to change the fold of a protein by changing a restricted set of residues. They also confirm the validity of the rules for stability of helical folds that have been obtained by analysis of experimentally determined protein structures. One obvious impliction of this work is that it might be possible, by just changing a few residues in Janus, to design a mutant that flip-flops between a helical and p sheet structures. Such a polypeptide would be a very interesting model system for prions and other amyloid proteins. 

Scott and Kucera [4] carried out some experiments that were designed to confirm that the two types of solute/stationary phase interaction, sorption and displacement, did, in fact, occur in chromatographic systems. They dispersed about 10 g of silica gel in a solvent mixture made up of 0.35 %w/v of ethyl acetate in n-heptane. It is seen from the adsorption isotherms shown in Figure 8 that at an ethyl acetate concentration of 0.35%w/v more than 95% of the first layer of ethyl acetate has been formed on the silica gel. In addition, at this solvent composition, very little of the second layer was formed. Consequently, this concentration was chosen to ensure that if significant amounts of ethyl acetate were displaced by the solute, it would be derived from the first layer on the silica and not the less strongly held second layer. 

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