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Delta-9 tetrahydrocannabinol

Lepore M, Vorel SR, Lowinson J, et al Conditioned place preference induced by delta-9-tetrahydrocannabinol comparison with cocaine, morphine, and food reward. LifeSci 56 2073-2080, 1995... [Pg.179]

Lichtman AH, Sheikh SM, Loh HH, et al Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice. J Pharmacol Exp Ther 298 1007—1014, 2001... [Pg.179]

Teesson M, Lynskey M, Manor B, et al The psychometric properties of BSM-IV cannabis use disorders. Brug Alcohol Bepend 68 235—262, 2002 Tsou K, Patrick SL, Walker JM. Physical withdrawal in rats tolerant to delta 9-tetrahydrocannabinol precipitated by a cannabinoid receptor antagonist. Eur J Pharmacol 280 R13-R15, 1995... [Pg.180]

McKallip RJ, Nagarkatti M, Nagarkatti PS. Delta-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. J Immunol 2005 174 3281-9. [Pg.165]

Miskin EM, Cabral GA. Delta-9-tetrahydrocannabinol decreases host resistance to herpes simplex virus type 2 vaginal infection in B6C3F mice. J Gen Virol 1985 66 2539-2549. [Pg.132]

Sim LJ, Hampson RE, Deadwyler SA, Childers SR. Effects of chronic treatment with delta-9-tetrahydrocannabinol on cannabinoid-stimulated [35S]GTPgamma-S autoradiography in rat brain. J Neurosci 1996 16 8057-8066. [Pg.152]

Burkey TH, Quock RM, Consroe P, Roeske WR, Yamamura HI. delta-9-Tetrahydrocannabinol is a partial agonist of cannabinoid receptors in mouse brain. Eur J Pharmacol 1997 323 R3-R4. [Pg.152]

Hollister LE, HK, G. The benzodiazepine receptor antagonist flumazenil does not block clinical effects of delta-9-tetrahydrocannabinol. Life Sci 1990 47 1655-1650. [Pg.152]

Schou J, Prockop LD, Dahlstrom G, Rohde C. Penetration of delta-9-tetrahydrocannabinol and ll-OH-delta-9-tetrahydrocannabinol through the blood-brain barrier. Acta Pharmacol Toxicol (Copenh) 1977 41 33-38. [Pg.152]

Bloom, A.S., Effect of delta-9-tetrahydrocannabinol on the synthesis of dopamine and norepinephrine in mouse brain synaptosomes, J. Pharmacol. Exp. Ther., 221, 97, 1982. [Pg.17]

Sakurai-Yamashita, Y., Kataoka, Y., Fujiwara, M., Mine, K., and Ueki, S., Delta 9-tetrahydrocannabinol facilitates striatal dopaminergic transmission, Pharmacol. Biochem. Behav., 33, 397, 1989. [Pg.17]

There are over 400 constituent compounds in marijuana. More than 60 of these are pharmacologically active cannabinoids, of which 4 are the most important. The most psychoactive is delta-9-tetrahydrocannabinol (A-9-THC). The other three important natural cannabinoids are A-8-THC, cannabinol and cannabidiol (Kumar et al., 2001). In addition, some of the metabolites of THC, such as 11-hydroxy-A-9-THC, are also psychoactive. As a consequence and contrary to many other drugs, the metabolism of THC in the liver does not decrease intoxication, rather it prolongs it. [Pg.89]

Lemberger L, Tamarkin NR, Axelrod J and Kopin IJ (1971). Delta-9-tetrahydrocannabinol Metabolism and disposition in long-term marihuana smokers. Science, 2, 72-74. [Pg.272]

McLaughlin PJ, Delevan CE, Carnicom S, Robinson JK and Brener J (2000). Fine motor control in rats is disrupted by delta-9-tetrahydrocannabinol. Pharmacology, Biochemistry and Behaviour, 66, 803-809. [Pg.274]

Noyes R, Brunk SF, Avery DAH and Canter AC (1975b). The analgesic properties of delta-9-tetrahydrocannabinol and codeine. Clinical Pharmacology and Therapeutics, 18, 84-89. [Pg.276]

Cabral, G.A. et al., Effect of delta 9-tetrahydrocannabinol on herpes simplex virus type 2 vaginal infection in the guinea pig, Proc. Soc. Exp. Biol. Med., 182, 181, 1986. [Pg.538]

Specter, S., Lancz, G., Westrich, G., and Friedman, H., Delta-9-tetrahydrocannabinol augments murine retroviral induced immunosuppression and infection, Int. J. Immuno-pharmacol., 13,411, 1991. [Pg.538]

Newton, C.A., Klein, T.W., and Friedman, H., Secondary immunity to Legionella pneumophila and Thl activity are suppressed by delta-9-tetrahydrocannabinol injection, Infect. Immun., 62, 4015, 1994. [Pg.538]

Hine B. (1985). Morphine and delta 9-tetrahydrocannabinol two-way cross tolerance for antinociceptive and heart-rate responses in the rat. Psychopharmacology (Berlin). 87(1) 34-38. HokfeItT, Elde R, Johansson 0, Terenuis L, Stein L. (1977). The distribution of enkephalin-immunoreactive cell bodies in the rat central nervous system. Neurosci Lett. 5 25. [Pg.523]

Moss DE, Johnson RL. (1980). Tonic analgesic effects of delta 9-tetrahydrocannabinol as measured with the formalin test. EurJ Pharmacol. Feb. 8 61(3) 313-15. [Pg.527]

Pugh G Jr, Smith PB, Dombrowski DS, Welch SP. (1996). The role of endogenous opioids in enhancing the anti nociception produced by the combination of delta 9-tetrahydrocannabinol and morphine in the spinal cord. J Pharmacol Exp Ther. 279(2) 608-16. [Pg.529]

Reche I, Puentes JA, Ruiz-Gayo M. (1996). Potentiation of delta 9-tetrahydrocannabinol-induced analgesia by morphine in mice involvement of mu- and kappa-opioid receptors. EurJ Pharmacol. 318(1) 11-16. [Pg.529]

Smith PB, Martin BR. (1992). Spinal mechanisms of delta 9-tetrahydrocannabinol-induced analgesia. Brain Res. 578(1-2) 8-12. [Pg.531]

Smith PB, Welch SP, Martin BR. (1994). Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice. J Pharmacol Exp Then 268(3) 1381-87. [Pg.531]

Bonnin A, Fernandez-Ruiz JJ, Martin M, Rodriguez de Fonseca F, Flernandez ML, Ramos JA. (1993). Delta 9-Tetrahydrocannabinol affects mesolimbic dopaminergic activity in the female rat brain interactions with estrogens. J Neural Trans Gen Section. 92(2-3) 81-95. [Pg.556]

Chiu P, Olsen DM, Borys HK, Karler R, Turkanis SA. (1979). The influence of cannabidiol and delta 9-tetrahydrocannabinol on cotelt epilepsy in rats. Epilepsia. 20(4) 365-75. [Pg.557]

Cooler P, Gregg M. (1977). Effect of delta-9-tetrahydrocannabinol on intraocular pressure in humans. Southern Med J. 70(8) 951-54. [Pg.557]

Cutler MG, Mackintosh JH. (1984). Cannabis and delta-9-tetrahydrocannabinol. Effects on elements of social behaviour in mice. Neuropharmacology. 23(9) 1091-97. [Pg.557]

Dalterio S, Bartke A, Mayfield D. (1985a). Effects of delta 9-tetrahydrocannabinol on testosterone production in vitro influence of Ca++, Mg+-i-, or glucose. Life Sci. 37(15) 1425-33. [Pg.557]

Dalterio S, Mayfield D, Bartke A, Morgan W. (1985b). Effects of psychoactive and non-psychoactive cannabinoids on neuroendocrine and testicular responsiveness in mice. Life Sci. 36(13) 1299-306. Dalterio S, Steger R, Peluso J, de Paolo L. (1987). Acute delta 9-tetrahydrocannabinol exposure effects on hypothalamic-pituitary-testicular activity in mice. Pharmacol Biochem Behav. March 26(3) 533-37. [Pg.557]

Diaz S, Specter S, Coffey RG. (1993). Suppression of lymphocyte adenosine 3 5 -cyclic monophosphate (cAMP) by delta-9-tetrahydrocannabinol. Int J Immunopharmacol. 15(4) 523-32. [Pg.558]

Dittrich A, Battig K, von Zeppelin I. (1973). Effects of (-) delta-9-tetrahydrocannabinol (delta-9-THC) on memory, attention, and subjective state. Psychopharmacologia. 33 369-76. [Pg.558]

Feinberg I, Jones R, Walker JM, Cavness C, March J. (1975). Effects of high dosage delta-9-tetrahydrocannabinol on sleep patterns in man. din Pharmacoi Ther. 17(4) 458-66. [Pg.559]

Fride E. (1995). Anandamides tolerance and cross-tolerance to delta 9-tetrahydrocannabinol. Brain Res. 697(1-2) 83-90. [Pg.559]

Graceffo TJ, Robinson JK. (1998). Delta-9-tetrahydrocannabinol (THC) fails to stimulate consumption of a highly palatable food in the rat. Life Sci. 62(8) PL85-88. [Pg.560]

Heyser CJ, Hampson RE, Deadwyler SA. (1993). Effects of delta-9-tetrahydrocannabinol on delayed match to sample performance in rats alterations in short-term memory associated with changes in task specific firing of hippocampal cells. J Pharmacol Exp Ther. 264(1) 294-307. [Pg.560]

Hutcheson DM, Tzavara ET, Smadja C, Valjent E, Roques BP, Hanoune J, Maldonado R. (1998). Behavioural and biochemical evidence for signs of abstinence in mice chronically treated with delta-9-tetrahydrocannabinol. Br J Pharmacol. 125(7) 1567-77. [Pg.561]

Karler R, Calder LD, Sangdee P, Turkanis SA. (1984). Interaction between delta-9-tetrahydrocannabinol and kindling by electrical and chemical stimuli in mice. Neuropharmacology. 23(11) 1315-20. [Pg.561]

Karler R, Calder LD, Turkanis SA. (1986). Prolonged CNS hyperexcitability in mice after a single exposure to delta-9-tetrahydrocannabinol. Neuropharmacology. 25(4) 441-46. [Pg.561]

Matsuzaki M, Casella GA, Ratner M. (1987). delta 9-Tetrahydrocannabinol EEG changes, bradycardia, and hypothermia in the rhesus monkey. Brain Res Bull. 19(2) 223-29. [Pg.562]

McMillan DE, Snodgrass SH. (1991). Effects of acute and chronic administration of delta 9-tetrahydrocannabinol or cocaine on ethanol intake in a rat model. Drug Alcohol Dependence. 27(3) 263-74. [Pg.562]

Murillo-Rodriguez E, Sanchez-Alavez M, Navarro L, Martinez-Gonzalez D, Drucker-Colin R, Prospero-Garcia 0. (1998). Anandamide modulates sleep and memory in rats. Brain Res. 812(1-2) 270-74. Murphy LL, Gher J, Steger RW, Bartke A. (1994). Effects of delta 9-tetrahydrocannabinol on copulatory behavior and neuroendocrine responses of male rats to female conspecifics. Pharmacol Biochem Behav. 48(4) 1011-17. [Pg.563]

Murphy LL, Newton SC, Dhali J, Chavez D. (1991). Evidence for a direct anterior pituitary site of delta-9-tetrahydrocannabinol action. Pharmacol Biochem Behav. 40(3) 603-7. [Pg.563]

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Delta

Preparing Delta-9-Tetrahydrocannabinol

Tetrahydrocannabinol

Tetrahydrocannabinolic

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