Copulatory behavior

Behavioral effects were noted when reproductive function was assessed in male Long-Evans rats that were given trichloroethylene in com oil by gavage for 6 weeks (Zenick et al. 1984). Copulatory behavior was decreased at 1,000 ppm, and the study authors attributed this to the narcotic properties of trichloroethylene. Sperm count, motility, or morphology were not affected in these rats. The time between dosing and observation of copulatory behavior was not stated. 

A relatively old compound, p-chlorophenylalanine (74), is able to penetrate the blood-brain barrier into the CNS and serves as a serotonin inhibitor. Interestingly, it increases copulatory behavior in... 

Dewsbury, D.A. (1982) Dominance rank, copulatory behavior, and differential reproduction. Quart. Rev. Biol. 57, 135-159. 

Murphy LL, Cadena RS, Chavez D, Ferraro JS. (1998). Effect of American ginseng (Panax quinquefolium) on male copulatory behavior in the rat. Physiol Behav. 64(4) 445-50. 

Murillo-Rodriguez E, Sanchez-Alavez M, Navarro L, Martinez-Gonzalez D, Drucker-Colin R, Prospero-Garcia 0. (1998). Anandamide modulates sleep and memory in rats. Brain Res. 812(1-2) 270-74. Murphy LL, Gher J, Steger RW, Bartke A. (1994). Effects of delta 9-tetrahydrocannabinol on copulatory behavior and neuroendocrine responses of male rats to female conspecifics. Pharmacol Biochem Behav. 48(4) 1011-17. 

Dewsbury, D. A. (1981). Effects of novelty on copulatory behavior. PsychologicalBulletin 89, 464-482. 

Androgenic stimulation of the MPOA often stimulates the display of male-typical behaviors. The MPOA is consistently androgen-responsive and has been implicated in different species in the motor performance of copulatory behavior (Christensen and Clemens, 1974), scent marking (Thiessen and Yahr, 1970), and aggressive behaviors. The MPOA may be involved in appetitive sexual motivation, although several studies point to the amygdala s performance in this role. 

In sustained-flight wind tunnel experiments, it appeared that synthetic E/Zl 1-14 Aid s were equivalent in "attraction" to virgin females (22). Furthermore, in response to these two primary components, some males demonstrated a full range of pre-copulatory behaviors, e.g. upwind flight, courtship and copulatory attempts similar to that when they responded to "calling" virgin females (26). Therefore, it seemed... 

W. R. Anderson, J. W. Simpkins, M. E. Brewster, and N. Bodor, Evidence for the reestablishment of copulatory behavior in castrated male rats with a brain-enhanced estradiol-chemical delivery system, Pharmacol. Biochem. Behav. 27 265 (1987). 

Huyton P. M. and Langley P. A. (1982) Copulatory behavior of the tsetse flies Glossina morsitans and G. austeni. Physiol. Entomol. 7, 167-174. 

Stoffolano J. G., Schauber E., Yin C. M., Tillman J. A. and Blomquist G. J. (1997). Cuticular hydrocarbons and then role in copulatory behavior in Phormia regina (Meigen). J. Insect Physiol. 43, 1065-1076. 

Such effects have been little studied in other dipteran species, but the principal CHC of G. morsitans morsitans males, 19,23-dimethyltritriacont-l-ene, strongly inhibits male copulatory behavior (Carlson and Schlein, 1991), and may play a role in restricting male-male interactions in this species. 

Putnam SK, Du J, Sato S, Hull EM (2001) Testosterone restoration of copulatory behavior correlates with medial preoptic dopamine release in castrated male rats. Horm Behav 39 216-224. 

Gray GD, Zerylnick M, Davis HN, Dewsbury DA. Effects of variations in the male copulatory behavior on ovulation and implantation in prairie voles, Microtus ochrogaster. Horm. Behav. 1974 5 389-396. 

Kimura et al. 1987) although its action on male sexual responses is not known. Nevertheless, this pathway could provide the neuroendocrine and anatomical substrates to regulate copulatory behavior in male rats. 

Murphy LL, Gher J, Steger RW, Bartke A. Effects of A -tetrahydrocannabinol on copulatory behavior and neuroendocrine responses of male rats to female conspecifics. Pharmacol. Biochem. Behav. 48, 1011-1017 (1994). 

Gray, G. D., and Dewsbury, D., 1975, A quantitative analysis of copulatory behavior in the meadow vole, Microtus pennsylvanicus, Anim. Bdiav. 23260-267. 

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