Cystic fibrosis-related diabetes

Moran A, Phillips J, Milla C. Insulin and glucose excursion following premeal insulin lispro or repaglinide in cystic fibrosis-related diabetes. Diabetes Care 2001 24(10) 1706-1710. 

The effect of nebulized salbutamol 2.5 mg on blood glucose concentration has been assessed in a doubleblind, placebo-controlled study in 19 patients with insulin-dependent diabetes (9 of whom had cystic fibrosis-related diabetes) (1053). There were no significant... 

Wilson DC, Kalnins D, Stewart C, et al. Challenges in the dietary treatment of cystic fibrosis related diabetes mellitus. Clin Nutr 2000 19 87-93. 

Insulin lispro and repaglinide were given to seven patients with diabetes related to cystic fibrosis (26). They had normal fasting blood glucose and insulin concentrations, but postprandial glucose concentrations were substantially raised. Insulin lispro had a larger and more... 

Abbreviations AMD, age-related macular degeneration HC, Hepatitis C DB, Diabetes HD, Huntington s Disease RSV, Respiratory Syncytial Virus DR, diabetic retinopathy DME, diabetic macular edema SCI, Spinal Cord Injury, INFL, Influenza CF, Cystic Fibrosis PD, Parkinson s Disease HIV, Human Immunodeficiency Virus ALS, amyotrophic lateral sclerosis CMV, Cytomegalovirus. 

Elevated levels of 8-oxodGua were found in the urine and lung tissues of smokers [ 17] as well as in body fluids and DNA from human tissues of patients with disorders such as cancer, atherosclerosis, chronic hepatitis, cystic fibrosis, diabetes, acquired immunodeficiency syndrome, neurodegenerative and age-related diseases [18]. 

The first report of insulin iontophoresis was not related to diabetes management. It was an attempt to see if insulin could affect the saline content of sweat in cystic fibrosis patients (Shapiro et al, 1975). A decrease in sweat chloride was observed after insulin iontophoresis however, the role of the insulin, and whether insulin reached the circulatory system for systemic effect, was not clear. 

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