Reaction cyclohexanone

Caprolactam [105-60-2] (2-oxohexamethyleiiiiriiQe, liexaliydro-2J -a2epin-2-one) is one of the most widely used chemical intermediates. However, almost all of the aimual production of 3.0 x 10 t is consumed as the monomer for nylon-6 fibers and plastics (see Fibers survey Polyamides, plastics). Cyclohexanone, which is the most common organic precursor of caprolactam, is made from benzene by either phenol hydrogenation or cyclohexane oxidation (see Cyclohexanoland cyclohexanone). Reaction with ammonia-derived hydroxjlamine forms cyclohexanone oxime, which undergoes molecular rearrangement to the seven-membered ring S-caprolactam. 

In this stage, the conversion of Co(II) to Co(III) is indicated by the rapid rise in the electrode potential, and fast generation of Co(III) accelerates the formation of HOK. Finally, in the third stage the accumulated Co(III) oxidizes the organic substrates to radical intermediates, while itself is reduced back to Co(II). Because of the noted complexity, the oscillation model for the cyclohexanone reaction was not elaborated upon in detail. 

The yield of the tricyclic IV/108 increases in the presence of Li+ instead of Na+ while that of the 2-phenylketone, IV/107, decreases (see Scheme IV/17 for the cyclohexanone reaction). Because of its better oxygen complexing ability the... 

Using the same procedure, a sample of poly (DHA-co-NVP) with 20 mole % DHA was rearranged in refluxing cyclohexanone (Reaction 2). A sample... 

This experiment describes the lithiation of allyl trimethylsilane and the conversions of the lithio compound with trimethylchlorosilane and cyclohexanone, reactions that proceed with very high y-selectivity. For functionalizations with other electrophiles, e.g., epoxides, alkyl halides, and carbon dioxide, see Ref. [1] and literature cited in this paper. 

Enolates react with sulfenyl halides to give an a-alkylthio ketone. As shown for cyclohexanone, reaction with LDA followed benzenesulfenyl chloride (PhSCl) produced phenylthio derivative 109. The proton adjacent to both the carbonyl and the sulfur (the a-proton) was more acidic and it was deprotonated with potassium hydride, forming the enolate, and alkylation with iodobutane gave a 91% yield of 110. As mentioned in Chapter 2, the sulfide moiety can be oxidized to a sulfoxide and thermally eliminated (syn elimination, sec. 2.9.C.v) to give an alkene. 9 Similar methodology can be applied to selenides, R—Se—R. O... 

Dimethyl ami no)benzaldehyde 100-19-6. Methyl 4-nitrophenyl ketone 100-52-7. Benzaldehyde. reactions 108-94-1. Cyclohexanone, reactions 121-33-5. 3-Methoxy-4-hydroxybenzaldehyde 122-00-9. Methyl 4-methyl phenyl ketone 12 3-08-0. 

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