Curcumin wound healing

Curcumin also enhances wound healing in diabetic rats and mice (Sidhu et al., 1999) and in H202-induced damage in human keratinocytes and fibroplasts (Phan et al., 2001). The wound healing effect is expressed by inhibiting the activation of NF-kappaB transcription factor through the prevention of the p65 unit of the factor. 

Phan, T.T., See, P., Lee, S.T. and Chan, S.Y. (2001) Protective effects of curcumin against oxidative damage on skin cell in vitro its implication for wound healing. Journal of Trauma 51, 927-931. 

Sidhu, G.S. et a/. (1999) Curcumin enhances wound healing in streptozotocin induced diabetic rats and genetically diabetic mice. Wound Repair and Regeneration 7, 362-374. 

Mani, H., Sidhu, G.S., Kumari, R., Gaddipati, J.P., Seth, P., and Maheshwari, R.K., Curcumin differentially regulates TGF-betal, its receptors and nitric oxide synthase during impaired wound healing. Biofactors, 16 (1-2), 29 3, 2002. 

Curcumin Turmeric root Anticancer, antioxidant, lower blood cholesltaol, promotes wound healing, prevents skin wrinkling, inhibits inflammation... 

Turmeric/curcumin are potential agents for wound healing. The therapeutic mechanism of wound healing has been studied by examining the antioxidant effects of curcumin on hydrogen peroxide induced damage to cultured human keratinocytes and fibroblasts (Phan et al 2001). Exposure of human keratinocytes and human dermal fibroblasts to cur-... 

The genus Curcuma includes some 30 species, native to India and the southeast of Asia. An extract is produced from the rhizomes, whose main components are curcumin and its derivatives. This extract has well-known anti-inflammatory, antioxidant, wound healing, anti-microbial and tyrosinase inhibitory properties. Its versatility makes it suitable for a number of cosmetic formulations on the basis of its anti-ageing, photo-protective, sensitive skin treatment, skin whitening, antiseptic and insect-repellent properties (Srimal, 1997). 

Healing of skin excision wounds as well as pepfic ulcers have recenfly been reported for furmeric and curcumin. 

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